Measurement of^(232)Th(p,x)^(225)Ac reaction cross section at CSNS APEP facility up to 80 MeV  

作　　者：Bing Jiang Bin-Bin Tian Han-Tao Jing Qi-Fan Dong Lu Guo 

机构地区：[1]Spallation Neutron Source Science Center,Dongguan 523803,China [2]Institute of High Energy Physics,Chinese Academy of Sciences(CAS),Beijing 100049,China [3]University of Chinese Academy of Sciences,Beijing 100049,China

出　　处：《Nuclear Science and Techniques》2025年第3期167-177,共11页核技术(英文)

基　　金：supported by the National Natural Science Foundation of China(No.12075135);the National Natural Science Foundation of China(No.12375127)。

摘　　要：The radioisotope actinium-225(^(225)Ac)has been successfully used for targeted alpha therapy in preclinical and clinical applications because of its excellent nuclear characteristics.Medium-and high-energy proton-spallation reactions on thorium are the most important methods for producing^(225)Ac.This study examines the possibility of producing^(225)Ac by irradiating thorium oxide with medium-energy protons.Thorium-oxide sheets were irradiated with 40-,50-,60-,70-,and 80-Me V protons on the Associated Proton-beam Experiment Platform(APEP)of the China Spallation Neutron Source(CSNS).The cross sections for the formation of^(225)Ac were measured using the activation method and offline gamma-ray spectrometric technique.The experimental results were compared with the existing data from EXFOR as well as the theoretical data from the TALYS-based evaluated nuclear-data library.Based on the experimental cross section and theoretical calculations,the production yield of^(225)Ac in the irradiated thorium targets was examined.The results showed that APEP can produce sufficient quantities of^(225)Ac for purification and clinical therapy.This work is the first measurement of proton-induced nuclearreaction cross sections at the CSNS APEP.

关 键 词：^(232)Th target Proton irradiation ^(225)Ac producing cross section 

分 类 号：O57[理学—粒子物理与原子核物理]