2023年洛阳市男男性行为者暴露前预防知晓和使用情况及影响因素  

Awareness and utilization of pre-exposure prophylaxis(PrEP)among men who have sex with men(MSM)in Luoyang City in 2023

作　　者：李亚静 麻小龙[1] 朱鑫[1] 李永超 马彦民[2] LI Yajing;MA Xiaolong;ZHU Xin;LI Yongchao;MA Yanmin(Luoyang Center for Disease Control and Prevention,Luoyang,Henan 471000,China;Henan Provincial Center for Disease Control and Prevention)

机构地区：[1]洛阳市疾病预防控制中心,河南洛阳471000 [2]河南省疾病预防控制中心

出　　处：《现代疾病预防控制》2025年第2期144-149,158,共7页MODERN DISEASE CONTROL AND PREVENTION

基　　金：河南省医学科技攻关计划(联合共建)项目(LHGJ20220179)。

摘　　要：目的 了解洛阳市男男性行为者(MSM)对暴露前预防(Pr EP)的知晓和使用情况及影响因素,为Pr EP在MSM中的推广实施提供依据。方法 2023年,依托男男社会组织采用“问卷星”电子问卷收集洛阳市MSM人口学特征、行为学信息、Pr EP知晓和使用情况等资料,应用多因素logistic回归确定与Pr EP认知和应用的相关因素。结果 填写有效问卷335人,洛阳市MSM对Pr EP的知晓率为29.3%(98/335),使用率为9.9%(33/335)。多因素logistic回归分析结果显示,以18~<31岁为参照,年龄31~<41岁(OR=3.047,95%CI:1.358~6.832)、41~<51岁(OR=4.496,95%CI:1.520~13.302)对Pr EP有较高的知晓率。近6个月MSM性行为时每次都用安全套者较近6个月从未使用安全套,显示更高的知晓率(OR=4.702,95%CI:1.332~16.598)。相反,通过线下方式寻找男性性伴(OR=0.440,95%CI:0.203~0.954)、近6个月未使用过新型毒品(OR=0.055,95%CI:0.005~0.658)、近6个月未了解性伴感染状况(OR=0.129,95%CI:0.044~0.376)及未听说过PEP (OR=0.171,95%CI:0.084~0.351)的MSM对Pr EP知晓率更低。MSM使用过PEP (OR=5.138,95%CI:1.849~14.273)、知晓Pr EP(OR=3.532,95%CI:1.259~9.909)的Pr EP使用率更高;与18~<31岁年龄组MSM相比,年龄31~<41岁(OR=0.119,95%CI:0.029~0.496)的Pr EP使用率更低。结论 洛阳市MSM对Pr EP的知晓率和使用率较低,要加大Pr EP服务的宣传推广力度,重点关注通过线下方式寻找男性性伴、未使用过新型毒品、未了解性伴感染状况、未听说过PEP、年龄在31~<41岁的MSM人群,提高重点人群Pr EP的知晓及使用,减少HIV/AIDS新发感染。Objective This study aimed to assess the awareness and utilization of pre-exposure prophylaxis(Pr EP) among men who have sex with men(MSM) in Luoyang City in 2023, so as to identify influencing factors to inform Pr EP promotion and implementation strategies. Methods Data on demographic characteristics, behavioral information, and Pr EP awareness and usage were collected through the "Questionnaire Star" electronic questionnaire distributed by social organizations. A multivariable regression analysis was conducted to identify factors associated with Pr EP awareness and usage. Results Out of 335 valid respondents, 29.3%(98/335) were aware of Pr EP, and 9.9%(33/335) reported using it. Multivariable logistic regression revealed that MSM aged 31-<41 years(OR=3.047, 95% CI: 1.358-6.832) and 41-<51 years(OR=4.496, 95% CI: 1.520-13.302) had higher Pr EP awareness compared to those aged 18-<31 years. MSM who consistently used condoms during the last 6 months(OR=4.702,95% CI: 1.332-16.598) also showed higher awareness compared to those who never used condoms during the last 6 months.Conversely, those who seeking male sexual partners offline(OR=0.440, 95% CI: 0.203-0.954), not using new drugs in the past 6months(OR=0.055, 95%CI: 0.005-0.658), unaware of their sexual partners' infection status(OR=0.129, 95%CI: 0.044-0.376)and unfamiliar with post-exposure prophylaxis(PEP)(OR=0.171, 95%CI: 0.084-0.351) had lower Pr EP awareness. MSM who had used PEP(OR=5.138, 95%CI: 1.849-14.273) and were aware of Pr EP(OR=3.532, 95%CI: 1.259-9.909) had higher usage rates. However, MSM aged 31-<41 years had a lower Pr EP usage rate compared to those aged 18-<31 years(OR=0.119, 95%CI:0.029-0.496). Conclusions Pr EP awareness and usage among MSM in Luoyang City are generally low. Targeted promotion and publicity efforts are needed, particularly for MSM aged 31-<41 who seek partners offline, do not used new drugs, are unaware of their partners' infection status, are unfamiliar with PEP or have not been exposed to it. These efforts could enhance P

关 键 词：男男性行为者 暴露前预防 艾滋病 性传播疾病 

分 类 号：R512.91[医药卫生—内科学]