妊娠期体重增加对GDM患者母婴不良结局的影响  

Effects of the weight gain of pregnant women with gestational diabetes mellitus during pregnancy on the adverse maternal and infant outcomes

作　　者：吕旭明 何蕊蕊 LV Xuming;HE Ruirui(Xuancheng Central Hospital,Xuancheng,Anhui Province,242000)

机构地区：[1]安徽省宣城市中心医院,242000

出　　处：《中国计划生育学杂志》2025年第3期714-717,共4页Chinese Journal of Family Planning

摘　　要：目的:评估妊娠糖尿病(GDM)患者妊娠期体重增加对母婴不良结局的影响。方法:回顾性收集2022年6月-2024年6月本院定期产前检查并分娩的GDM孕妇143例临床资料,按照是否发生母婴不良结局分为不良结局组56例和非不良结局组87例。比较两组一般资料、妊娠早期生理状态、妊娠期体重增加(GWG)、妊娠期血糖控制方式和分娩情况。采用logistic回归分析GWG对母婴不良结局的影响。结果:影响GDM患者母婴不良结局的因素包括年龄大、孕前体质指数(BMI)达到“超重/肥胖”标准、FPG升高、HOMA-IR升高、妊娠期GWG达到“过度”标准、饮食疗法控制血糖,OR分别为1.084、3.831、2.176、1.837、4.668和0.361,其中饮食疗法为保护因素,其他为危险因素。结论:GDM患者妊娠期体重增加过度,会大幅度提高母婴不良结局风险,应重点关注并干预。Objective:To evaluate the effects of the weight gain of pregnant women with gestational diabetes mellitus(GDM)during pregnancy on the adverse maternal and the infant outcomes.Methods:The clinical data of 143 pregnant women with GDM who were regularly examined and delivered in the hospital from June 2022 to June 2024 were collected retrospectively.The women were divided into group A(56 cases with the adverse pregnancy outcomes)and group B(87 cases without the adverse pregnancy outcomes)according to whether the adverse pregnancy outcomes of the women occurred or not.The general data,the physiological status during the first trimester of pregnancy,the weight gain during pregnancy(GWG),the blood glucose control model during pregnancy and the delivery situation of the women were compared between the two groups.Logistic regression analysis was used to evaluate the effects of GWG of the women with GDM on the adverse maternal and infant outcomes.Results:The influencing factors of the adverse maternal and infant outcomes of pregnant women with GDM included the advance age,the overweight/obesity standard in the pre-pregnancy body mass index(BMI),the elevated fasting plasma glucose(FPG)level and homeostasis model assessment of insulin resistance(HOMA-IR)value,the excessive GWG during pregnancy and the diet therapy to control blood glucose level(OR 1.084,3.831,2.176,1.837,4.668 and 0.361).And among them,the diet therapy of the women was the protective factor of their adverse maternal and infant outcomes,and the others factors were the risk factors of their adverse maternal and infant outcomes.Conclusion:The excessive GWG of the pregnant women with GDM will greatly increase the risk of the adverse maternal and infant outcomes,and which should be focused on and the intervention should be given to these women.

关 键 词：妊娠期糖尿病 妊娠期体重增加 母婴不良结局 影响因素 

分 类 号：R71[医药卫生—妇产科学]