肠内营养剂联合复方聚乙二醇电解质散方案对不同危险分层人群肠道准备质量的影响  

Effect of O′Haine combined with polyethylene glycol on the quality of bowel preparation in different risk stratified population

作　　者：刘雪平 赵文月 崔继燕 刘娓娓 LIU Xue-ping;ZHAO Wen-yue;CUI Ji-yan;LIU Wei-wei(Department of Gastroenterology,Shandong Provincial Third Hospital,250000Jinan,China)

机构地区：[1]山东省立第三医院消化内科,山东济南250000

出　　处：《临床消化病杂志》2025年第1期35-38,共4页Chinese Journal of Clinical Gastroenterology

摘　　要：[目的]比较奥海恩联合复方聚乙二醇电解质散(PEG)方案对不同危险分层人群肠道准备质量的影响。[方法]将198例行结肠镜检查患者随机分为实验组(100例)和对照组(98例)。2组患者均根据Dik VK预测模型进行风险分层。对照组所有患者均常规低渣饮食,并采用分次口服3LPEG方案(检查前一天晚上服用1L,检查的当天上午服用2L)。实验组给予肠内营养剂代替低渣饮食,肠道准备失败高风险患者采取分次口服3LPEG的方案进行肠道准备(检查前一天晚上服用1L,检查的当天上午服用2L);肠道准备失败低风险患者在检查当天上午服用2LPEG。肠道清洁度采用波士顿量表评分(BBPS),记录是否检出大肠息肉、不良反应、进镜时间。[结果]实验组与对照组肠道准备成功率、肠道准备失败高风险人群肠道准备成功率、BBPS评分总分及左半结肠、中段结肠及右半结肠评分比较,差异有统计学意义(P<0.001);进镜时间比较,差异有统计学意义;2组息肉检出率、不良反应比较,差异无统计学意义(P>0.05)。[结论]奥海恩联合PEG方案能提高肠道准备失败高风险人群的肠道准备质量,降低肠道准备失败低风险人群复方PEG的服药量,提高肠道准备整体质量。[Objective]To evaluate the efficacy of O′Haine combined with polyethylene glycol for bowel preparation before colonoscopy in patients with different risks..[Methods]A total of 198patients who underwent colonoscopy were randomly assigned to experimental group and control group.One hundred cases in experimental group,98cases in control group.Patients in both groups were risk stratified according to the Dik VK prediction model.In the control group,all patients were on a regular low-fiber diet with a splitdose oral 3LPEG regimen(1Lthe night before the examination and 2Lthe morning of the examination).In the experimental group,enteral nutrition was given instead of low-fiber diet,and the high-risk patients were given oral 3LPEG in fractional doses for bowel preparation(1Lon the night before examination and 2Lon the morning of examination).Low-risk patients were given 2LPEG on the morning of the examination.The intestinal cleanliness was assessed by Boston Bowel preparation Score(BBPS),and the detection of intestinal polyps,adverse reactions,and cecal intubation time were recorded.[Results]There were statistically significant differences between the two groups in the success rate of bowel preparation,the success rate of bowel preparation in high-risk groups,the total BBPS score,the scores of left colon,middle colon and right colon(P<0.001).There was a statistically significant difference in cecal intubation time.There was no significant difference in polyp detection rate and adverse reactions between the two groups(P>0.05).[Conclusion]O′Haine combined with polyethylene glycol can improve the quality of bowel preparation in people with high risk of bowel preparation failure,reduce the dosage of polyethylene glycol in people with low risk of bowel preparation failure,and improve the overall quality of bowel preparation.

关 键 词：结肠镜术 危险分层 肠道准备 波士顿肠道准备量表 

分 类 号：R656.9[医药卫生—外科学]