A型肉毒毒素治疗面部痤疮机制与临床应用研究进展  

Research progress on the mechanism and clinical application of botulinum toxin type A in the treatment of facial acne

作　　者：胡雅坤 粟倩雅 王飞[1] HU Yakun;SU Qianya;WANG Fei(Department of Dermatology,Zhongda Hospital,Southeast University,Nanjing 210009,China)

机构地区：[1]东南大学附属中大医院皮肤科,江苏南京210009

出　　处：《中国美容整形外科杂志》2025年第2期79-81,102,共4页Chinese Journal of Aesthetic and Plastic Surgery

摘　　要：痤疮是临床最常见的皮肤病之一,传统治疗方法为局部治疗或系统治疗。近年来,A型肉毒毒素(botulinum toxin type A,BTX-A)通过减少皮脂的产生与分泌,调节炎症反应,抑制皮脂腺导管过度角化等多个环节发挥作用,为痤疮治疗带来新的方向。现对BTX-A治疗面部痤疮的机制及疗效作一综述,以期为临床应用提供更多依据。Acne is one of the most common skin diseases in clinical practice,and traditional treatment methods include local or systemic therapy.In recent years,studies have shown that botulinum toxin type A(BTX-A)can effectively treat acne.BTX-A exerts its effects through multiple mechanisms,including reducing sebum production and secretion,modulating inflammatory responses,and inhibiting hyperkeratinization of sebaceous ducts,thus bringing a new direction to acne treatment.This article reviews the mechanism and efficacy of BTX-A in the treatment of facial acne,aiming to provide more evidence for clinical application.

关 键 词：A型肉毒毒素 痤疮 治疗 

分 类 号：R758.733[医药卫生—皮肤病学与性病学]