参附注射液在急性心肌梗死并发休克阳脱证患者中的应用价值  

Application Value of Shenfu Injection in Patients with Acute Myocardial Infarction Complicated by Shock Yang Withdrawal Syndrome

作　　者：古灵灵 廖桂娇 卢燕玲 聂鲱荣 GU Lingling;LIAO Guijiao;LU Yanling;NIE Feirong(Department of Critical Care Medicine,Wuzhou Hospital of Traditional Chinese Medicine,Wuzhou 543000,Guangxi Zhuang Autonomous Region,China)

机构地区：[1]梧州市中医医院重症医学科,广西梧州543000

出　　处：《世界复合医学(中英文)》2024年第11期49-53,共5页World Journal of Complex Medicine

摘　　要：目的探讨参附注射液在急性心肌梗死(acute myocardial infayction,AMI)并发休克阳脱症患者中的临床价值。方法回顾性选取2022年8月—2023年4月梧州市中医医院收治的80例AMI并发休克阳脱证患者的临床资料,按照治疗方法不同分为两组,各40例。对照组采用常规西药(阿司匹林)治疗,观察组采用常规西药联合参附注射液治疗。比较两组患者的临床疗效、血流速度(blood flow velocity,Vp)、舒张期血流速度(diastolic blood flow velocity,Vd)、阻力指数(resistance index,RI)、搏动指数(pulsatility index,PI)、左心室射血分数(left ventricle ejection fraction,LVEF)、每搏输出量(stroke volume,SV)、左心室末期内径(left ventricular end-systolic diameter,LVESD)与中医证候积分。结果观察组治疗总有效率为90.00%(36/40),高于对照组的72.50%(29/40),差异有统计学意义(χ^(2)=4.021,P<0.05)。治疗后,观察组LVEF水平高于对照组,SV、LVESD水平均低于对照组,差异有统计学意义(P均<0.05)。治疗后,观察组Vp、Vd均高于对照组,RI、PI均低于对照组,差异有统计学意义(P均<0.05)。治疗后,观察组中医证候积分均低于对照组,差异有统计学意义(P均<0.05)。结论参附注射液能够提升AMI并休克阳脱症患者的临床疗效,减轻患者的心肌缺血损伤,改善脑氧代谢和临床症状。Objective To investigate the clinical value of Shenfu injection in patients with acute myocardial infarction(AMI)complicated with shock yang prolapse.Methods The clinical data of 80 patients with AMI complicated with shock yang detachment syndrome admitted to Wuzhou Hospital of Traditional Chinese Medicine from August 2022 to April 2023 were retrospectively selected and divided into two groups according to different treatment methods,with 40 cases in each group.The control group was treated with conventional western medicine(aspirin),and the observation group was treated with conventional western medicine combined with Shenfu Injection.The clinical efficacy,blood flow velocity(Vp),diastolic blood flow velocity(Vd),resistance index(RI),pulsatility index(PI),left ventricle ejection fraction(LVEF),stroke volume(SV),left ventricular endsystolic diameter(LVESD)and traditional Chinese medicine syndrome scores were compared between the two groups.Results The total effective rate of treatment in the observation group was 90.00%(36/40),which was higher than 72.50%(29/40)in the control group,and the difference was statistically significant(χ^(2)=4.021,P<0.05).After treatment,the LVEF level of the observation group was higher than that of the control group,and the SV and LVESD levels were lower than those of the control group,and the differences were statistically significant(all P<0.05).After treatment,the Vp and Vd of the observation group were higher than those of the control group,and the RI and PI were lower than those of the control group,the differences were statistically significant(all P<0.05).After treatment,the traditional Chinese medicine syndrome scores of the observation group was lower than that of the control group,and the differences were statistically significant(all P<0.05).Conclusion Shenfu Injection can improve the clinical efficacy of patients with AMI and shock yang loss,reduce myocardial ischemia injury,and improve cerebral oxygen metabolism and clinical symptoms.

关 键 词：参附注射液 急性心肌梗死 休克阳脱症 心功能指标 

分 类 号：R542.22[医药卫生—心血管疾病]