寿胎丸联合燥湿化痰汤加减治疗PCOS不孕症(痰湿阻滞证)对子宫内膜容受性及临床妊娠的影响  

The effect of Shoutai Pill combined with Zaoshi Huatan Decoction on endometrial receptibility and clinical pregnancy of polycystic ovary syndrome infertility(phlegm-dampness obstruction syndrome)

作　　者：熊芳 杨晓燕 聂亚丽 XIONG FangA;YANG Xiaoyan;NIE Yali(Department of Reproductive Medicine,the Second Affiliated Hospital of Xingtai Medical College,Xingtai 054000,Hebei,China)

机构地区：[1]邢台医学高等专科学校第二附属医院生殖医学科,河北邢台054000

出　　处：《中国性科学》2025年第3期132-137,共6页Chinese Journal of Human Sexuality

基　　金：邢台重点研发计划自筹项目(2020ZC361)。

摘　　要：目的 探讨寿胎丸联合燥湿化痰汤加减治疗多囊卵巢综合征(PCOS)不孕症(痰湿阻滞证)对子宫内膜容受性及临床妊娠的影响。方法 选取2018年2月至2019年1月邢台医学高等专科学校第二附属医院收治的120例PCOS不孕症(痰湿阻滞证)患者作为研究对象,按照随机数字表法分为观察组和对照组,每组60例。对照组采用常规西医治疗,观察组在对照组基础上采用寿胎丸联合燥湿化痰汤加减治疗。比较两组临床疗效、治疗前后中医证候积分、性激素水平、子宫内膜容受性、排卵率及自然妊娠成功率。结果 治疗6个月后,观察组总有效率高于对照组(P<0.05)。治疗6个月后,两组主证、次证、总积分均低于治疗前,且观察组均低于对照组(P<0.05)。治疗6个月后,两组黄体生成素(LH)、卵泡刺激素(FSH)低于治疗前,且观察组低于对照组,两组孕酮(P)、雌二醇(E_2)高于治疗前,且观察组高于对照组(P<0.05)。治疗6个月后,两组阻力指数(RI)低于治疗前,且观察组低于对照组,两组子宫内膜厚度、搏动指数(PI)高于治疗前,且观察组子宫内膜厚度高于对照组(P<0.05)。观察组排卵率及自然妊娠成功率高于对照组(P<0.05)。结论 寿胎丸联合燥湿化痰汤加减治疗PCOS不孕症(痰湿阻滞证)效果良好,能够有效改善患者症状、性激素水平和子宫内膜容受性,提高排卵率和自然妊娠成功率。Objective To study the effects of Shoutai Pill combined with Zaoshi Huatan Decoction on endometrial receptibility and clinical pregnancy of polyeystic ovarysyndrome(PCOS)infertility(phlegm-dampness obstruction syndrome).MethodsA total of 120infertile patients(phlegm-dampness obstruction syndrome)with PCOS admitted to the Second Affiliated Hospital of Xingtai Medical College from February 2018 to January 2019 were included as study objects and separated into the observation group and the control group by random number table method,with 60 cases in each group.The control group were treated by conventional western medicine,and the observation group were treated by Shoutai Pill+Zaoshi Huatan Decoction based on the control group.The clinical efficacy,traditional Chinese medicine syndrome scores before and after treatment,sex hormones levels,endometrial receptibility,ovulation rate and natural pregnancy success rate were compared.Results After 6 months of treatment,the total effective rate in the observation group was higher than control group(P<0.05).The main and secondary syndrome score and total score after 6 months of treatment were significantly lower than those before treatment and the observation group were lower than the control group(P<0.05).Luteinizing hormone(LH)and follicle-stimulating hormone(FSH)after 6 months of treatment were significantly lower than those before treatment and the observation group were lower than the control group(P<0.05),while the levels of progesterone(P)and estradiol(Ez)were higher than before treatment and the observation group was higher than the control group(P<0.05).After 6 months of treatment,the resistance index(RI)of the two groups was lower than before treatment,and the observation group was lower,while the endometrial thickness and pulse index(PI)was higher than before treatment,and endometrial thickness in the observation group was higher than the control group(P<0.05).The ovulation rate and the success rate of natural pregnancy in the observation group were higher than th

关 键 词：寿胎丸 燥湿化痰汤 多囊卵巢综合征 不孕症 子宫内膜容受性 妊娠 

分 类 号：R711[医药卫生—妇产科学]