基于数据挖掘的裘生梁治疗慢性萎缩性胃炎肝胃气滞证用药规律及经验探究  

Exploring the Rule of Medication and Experience of QIU Shengliang’s Treatment of Liver and Stomach Qi Stagnation Syndrome of Chronic Atrophic Gastritis by Data Mining

作　　者：贺雨婷 洪千然 林伟业 孙可昕 裘生梁[1] HE Yuting;HONG Qianran;LIN Weiye(The First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Traditional Chinese Medicine),Hangzhou,310006,China;The First Clinical School of Zhejiang Chinese Medical University)

机构地区：[1]浙江中医药大学附属第一医院(浙江省中医院),杭州310006 [2]浙江中医药大学第一临床医学院

出　　处：《浙江中医药大学学报》2025年第2期172-178,共7页Journal of Zhejiang Chinese Medical University

基　　金：浙江省中医药科技计划项目(2022ZA056);浙江省新苗人才计划项目(2023R410006)。

摘　　要：[目的]运用数据挖掘技术探究裘生梁主任中医师(简称裘师)治疗慢性萎缩性胃炎(chronic atrophic gastritis,CAG)肝胃气滞证的用药规律及经验。[方法]收集2021年1月至2023年6月就诊于浙江省中医院裘师门诊的患者医案,设定纳入和排除标准、建立数据库、数据规范化处理,运用频数分析、构建中药矩阵进行聚类分析,结合裘师临床经验,对裘师治疗肝胃气滞型CAG的用药规律进行分析与归纳。[结果]涉及处方共162例,中药共171味;高频药物为厚朴、枳壳、姜半夏;其中药性以温为主,药味以辛、苦、甘为主,归经以胃、脾、肺、肝为主。复杂网络得出核心药组:半夏-厚朴-枳壳;聚类分析得出核心方为:姜半夏、厚朴、枳壳、香附、蒲公英、高良姜、刀豆、旋覆花、海螵蛸、水红花子、瓦楞子、刺猬皮、竹茹、木蝴蝶。[结论]裘师治疗CAG肝胃气滞证,善用益气温阳之品,治以理气和胃、化痰散结,注重阴阳调平、升降相因、燥湿相济、顾护正气,散中有和,和中有补,补中有清,方随法立,法从证来。[Objective]Using data mining technology to explore the medication rule and clinical experience of QIU Shengliang,Chief TCM physician(referred as Chief QIU),in treating chronic atrophic gastritis(CAG)with liver and stomach Qi stagnation syndrome.[Methods]By collecting data,setting up admission and discharge standards,establishing a database,standardizing data processing,conducting frequency analysis,constructing a Chinese medicine matrix and performing clustering analysis,combined with the clinical experience of Chief QIU,it conducted analysis and induction of his medication rules for CAG of liver and stomach Qi stagnation syndrome.[Results]This study involved 162 prescriptions,171 herbs.The high-frequency drugs were:Magnolia officinalis,Fructus aurantii,ginger pinellia;Among them,the medicinal properties were mainly warm,the medicinal tastes were mainly spicy,bitter and sweet,and the channels were mainly stomach,spleen,lung and liver.The core drug group was pinellia,Magnolia officinalis and Fructus aurantii.Cluster analysis showed that the core ingredients were:ginger pinellia,Magnolia officinalis,Fructus aurantii,dandelion,galangal,knife bean,spiral flower,cuttlebone,water red flower seed,corrugated seed,hedgehog skin,bamboo shavings and wood butterfly.[Conclusion]Chief QIU is skilled in treating CAG liver and stomach Qi stagnation syndrome.He often uses warm-tonifying herbs and prescribes treatments to regulate Qi and promote Yang,with a focus on resolving stagnation,harmonizing the stomach,dispersing phlegm and eliminating lumps.He emphasizes achieving balance between Yin and Yang,promoting the interaction between rising and descending Qi,harmonizing dryness and dampness,and nurturing the body’s vital energy.His prescriptions are tailored to the specific method,and the method is based on the patient’s symptoms.

关 键 词：慢性萎缩性胃炎 肝胃气滞证 数据挖掘 用药规律 名医经验 理气和胃 阴阳 裘生梁 

分 类 号：R256[医药卫生—中医内科学]