“东垣针法”指导下针刺配合西药治疗类风湿关节炎伴轻度贫血的临床观察  

Clinical Observation on Acupuncture Combined with Western Medicine in the Treatment of Rheumatoid Arthritis Complicated with Mild Anemia Under the Guidance of“Dongyuan Acupuncture”

作　　者：谭凤芝 余敏 张隆林 TAN Fengzhi;YU Min;ZHANG Longlin(Graduate School of Guangzhou University of Chinese Medicine,Guangzhou 510006 Guangdong,China;Dept.of Rheumatology,Chongqing Hospital of The First Affiliated Hospital of Guangzhou University of Chinese Medicine,Chongqing 400700,China)

机构地区：[1]广州中医药大学研究生院,广东广州510006 [2]广州中医药大学第一附属医院重庆医院风湿病科,重庆400700

出　　处：《广州中医药大学学报》2025年第4期907-913,共7页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：重庆市北碚区2024年川渝科技合作项目(编号:2024cykjhz-22)。

摘　　要：【目的】观察“东垣针法”指导下针刺配合西药治疗类风湿关节炎(RA)伴轻度贫血的临床疗效。【方法】选取2024年2月至2024年9月广州中医药大学第一附属医院重庆医院风湿病科病房及门诊收治的80例明确诊断为气血两虚证RA轻度贫血的患者为研究对象。按随机数字表将患者随机分为观察组和对照组,每组各40例。对照组给予西药常规治疗,观察组在对照组治疗的基础上,给予“东垣针法”指导下的针刺治疗。连续治疗4周。治疗1个月后,评价2组临床疗效,观察2组患者治疗前后中医证候积分和疼痛视觉模拟量表(VAS)评分的变化情况,以及疾病活动度评分(DAS-28)的情况,比较2组患者治疗前后类风湿因子(RF)、C反应蛋白(CRP)、血沉(ESR)、红细胞计数(RBC)、血红蛋白(Hb)水平的变化情况,并评价2组的安全性及不良反应的发生情况。【结果】(1)治疗后,观察组患者的中医证候积分明显改善(P<0.05),且观察组在改善患者的中医证候积分方面明显优于对照组,差异有统计学意义(P<0.05)。(2)治疗后,2组患者的VAS评分和DAS-28评分均明显改善(P<0.05),且观察组在改善VAS评分和DAS-28评分方面均明显优于对照组,差异均有统计学意义(P<0.05)。(3)治疗后,2组患者的RF、CRP、ESR水平均有明显改善(P<0.05),且观察组在改善RF、CRP、ESR水平方面均明显优于对照组,差异均有统计学意义(P<0.05);治疗后,观察组RBC水平有明显改善(P<0.05),但与对照组比较,差异无统计学意义(P>0.05);治疗后,2组患者的Hb水平有明显改善(P<0.05),且观察组在改善Hb水平方面明显优于对照组,差异有统计学意义(P<0.05)。(4)观察组总有效率为95.00%(38/40),对照组为87.50%(35/40);组间比较(秩和检验),观察组的疗效明显优于对照组,差异有统计学意义(P<0.05)。(5)观察组不良反应发生率为7.50%(3/40),对照组为27.50(11/40),组间比较,观察组的不良反应发生率明Objective To observe the clinical efficacy of acupuncture combined with western medicine in the treatment of rheumatoid arthritis(RA)complicated with mild anemia under the guidance of“Dongyuan acupuncture”.Methods A total of 80 cases of patients definitively diagnosed as RA complicated with mild anemia of deficiency of qi and blood were selected and randomly divided into the observation group and the control group according to the random number table method,those who were admitted to the wards and outpatient clinics of the Department.of Rheumatology,Chongqing Hospital of The First Affiliated Hospital of Guangzhou University of Chinese Medicine from February 2024 to September 2024,with 40 cases in each group.The control group was given conventional treatment with western medicines,while the observation group was additionally treated with acupuncture under the guidance of“Dongguan acupuncture”.The course of treatment covered four consecutive weeks.After one month of treatment,the clinical efficacy of the two groups was evaluated,and the changes in traditional Chinese medicine(TCM)syndrome scores and Visual Analogue Scale(VAS)of pain scores,as well as Disease Activity Scores(DAS-28)before and after treatment were observed in the two groups.The changes of rheumatoid factor(RF),C-reactive protein(CRP),erythrocyte sedimentation rate(ESR),red blood cell count(RBC),and hemoglobin(Hb)levels before and after treatment were compared between the two groups.The safety and incidence of adverse reactions in the two groups were also evaluated.Results(1)After treatment,the TCM syndrome scores of the patients in the observation group were improved significantly(P<0.05),and the improvement in the observation group was significantly superior to that in the control group,the difference being statistically significant(P<0.05).(2)After treatment,the VAS scores and DAS-28 scores of the patients in the two groups were improved significantly(P<0.05),and the improvement in the observation group was significantly superior to that in

关 键 词：东垣针法 针刺 类风湿关节炎 轻度贫血 临床观察 

分 类 号：R246.9[医药卫生—针灸推拿学]