Promising effects of Persian shallot extract on the serum markers and blood pressure of patients with metabolic syndrome:a double-blinded randomized controlled trial  

作　　者：Neda Naimipoor Zahra Bagheri-Hosseinabadi Mohammad Reza Hajizadeh Mitra Abbasifard Mohammad Reza Mirzaei Akram Ghadiri Anari Maryam Mohammad-Sadeghipour Mehdi Mahmoodi 

机构地区：[1]Department of Clinical Biochemistry,School of Medicine,Rafsanjan University of Medical Sciences,Rafsanjan 77181759,Iran [2]Department of Internal Medicine,School of Medicine,Ali-Ibn Abi-Talib Hospital,Rafsanjan University of Medical Sciences,Rafsanjan 7717937555,Iran [3]Molecular Medicine Research Center,Research Institute of Basic Medical Sciences,Rafsanjan University of Medical Sciences,Rafsanjan 7718175911,Iran [4]Diabetes Research Center,Shahid Sadoughi University of Medical Sciences,Yazd 8917693571,Iran [5]Department of Clinical Biochemistry,Afzalipour School of Medicine,Kerman University of Medical Sciences,Kerman 7616914115,Iran [6]Physiology Research Center,Institute of Neuropharmacology,Kerman University of Medical Sciences,Kerman 7619813159,Iran

出　　处：《Journal of Traditional Chinese Medicine》2025年第1期100-106,共7页中医杂志(英文版)

摘　　要：OBJECTIVE:To evaluate the effect of Persian shallot extract on the serum markers and blood pressure of patients with metabolic syndrome(MetS).METHODS:Fifty patients with Met S diagnosis were randomly assigned to the intervention(Persian shallot extract)and the control(placebo)group.Both groups received treatment for three months.Before the study and at the end of the study,5 mL peripheral blood was taken from each patient.The measured factors included total antioxidant capacity(TAC),superoxide dismutase enzyme(SOD),malondialdehyde,oxidized low-density lipoprotein(Ox-LDL),apolipoprotein H(Apo-H),fasting blood glucose(FBS),total cholesterol,triglycerides,high-density lipoprotein(HDL),LDL,and systolic and diastolic blood pressure.RESULTS:At baseline,the evaluated parameters were not significantly different between the intervention and control groups.At the end of the study,the mean serum levels of malondialdehyde and ox-LDL were significantly lower in the intervention group.The mean FBS,cholesterol,triglycerides,and LDL were significantly lower in the intervention group.The mean TAC and HDL were significantly higher in the intervention group(P<0.05).Moreover,the intervention group significantly reduced systolic and diastolic blood pressure.No other significant association was observed.CONCLUSION:Persian shallot extract has several beneficial effects in Met S patients,including optimizing oxidative balance,reducing blood pressure,fasting blood sugar,and blood lipid profile.

关 键 词：shallots medicine Persian metabolic syndrome ANTIOXIDANTS 

分 类 号：R73[医药卫生—肿瘤]