Effects of acupuncture combined with bone-setting therapy to treat tourette syndrome:a three-arm randomized controlled trial  

作　　者：LANG Jiawang JIN Lingqing LUO Jianchang LANG Boxu 

机构地区：[1]Department of Acupuncture and Massage,Municipal Hospital Affiliated to Medical School of Taizhou University,Taizhou 318000,China

出　　处：《Journal of Traditional Chinese Medicine》2025年第1期176-183,共8页中医杂志(英文版)

基　　金：Supported by Traditional Chinese medicine foundation of Zhejiang province:Clinical Study on the Correlation Between Tourette Syndrome and Anatomical Changes in the Atlantoaxial Joint(2010ZB162);Medical Health Science and Technology Project of Zhejiang Provincial Health Commission:Study on Protein Fingerprinting of Tourette Syndrome(2011KYB142);Renowned Traditional Chinese Medicine Expert Inheritance Studio Construction Project of Zhejiang province(No.GZS2020049);Key Disciplines of Traditional Chinese Medicine Foundation of Zhejiang Province(2012-XK-D20)。

摘　　要：OBJECTIVE:To explore the efficacy and safety of acupuncture combined with atlantoaxial joint bone-setting therapy for the treatment of Tourette syndrome.METHODS:We randomly divided 600 patients at a ratio of 1∶1∶1 into three groups:group A(acupuncture combined with atlantoaxial joint bone setting therapy group),group B(acupuncture group),and group C(tiapride group).After two months of treatment,the Yale global tic severity scale(YGTSS)score reduction,improvement in social function impairment,clinical efficacy,and long-term efficacy in the three groups were compared.RESULTS:After treatment,in the analysis of YGTSS score reduction,social function impairment improvement,the clinical control rate,and long-term efficacy,the results were all Group A>Group B>Group C,with a statistically significant difference(P<0.05).However,the total clinical efficacy of treatment in group A(94.9%)was not significantly different from that in group B(91.8%).Adverse reactions did not occur in groups A and B,and several adverse reactions occurred in 29%(n=58)of the group C patients.CONCLUSION:Compared with traditional drug therapy,acupuncture combined with atlantoaxial joint bone setting therapy has better clinical and long-term efficacy.This treatment strategy can improve the social function of children and prevent adverse reactions to drugs.

关 键 词：Tourette syndrome ACUPUNCTURE atlanto-axial joint tiapride hydrochloride bone setting randomized controlled trial 

分 类 号：R24[医药卫生—中医临床基础]