越婢加半夏汤治疗呼吸系统疾病研究进展  

Research progress in the treatment of respiratory diseases with Yuebi Jia Banxia Decoction

作　　者：张旭[1,2] 李素云 Zhang Xu;Li Suyun(Department of Respiratory Medicine,the First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450000,China;The First Clinical Medical College of Henan University of Chinese Medicine,Zhengzhou 450000,China)

机构地区：[1]河南中医药大学第一附属医院呼吸科,郑州450000 [2]河南中医药大学第一临床医学院,郑州450000

出　　处：《国际中医中药杂志》2025年第2期286-288,F0003,共4页International Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金(82074413);张仲景传承与创新专项(GZY-KJS-2022-041-1);河南省中医药科学研究选项课题(2022JDZX084)。

摘　　要：越婢加半夏汤出自《金匮要略》,其药味精简,适用于痰热内蕴、复感风邪之证。现代临床常运用其加减方联合西医疗法治疗支气管哮喘、COPD、肺炎、支气管炎、肺源性心脏病等呼吸系统疾病,可改善患者气喘、咳嗽、痰多等症状体征,降低气道高反应,抑制慢性炎症,提高肺功能,可有效减少复发,且安全性较好,作用机制可能与调节细胞因子水平,缓解气道炎症反应,改善免疫功能,调节多种氨基酸代谢水平,下调ERK、NF-κB表达,提高血清纤维连接蛋白水平有关。针对本方机制开展的实验研究较少,今后还需加强。Yuebi Jia Banxia Decoction comes from Jin Gui Yao Lue.Its medicinal taste is simple and suitable for the syndrome of internal heat retention and wind pathological factors.Modern clinical practice often uses its modified prescription combined with Western medicine therapy to treat respiratory diseases such as bronchial asthma,COPD,pneumonia,bronchitis,and pulmonary heart disease,which can improve symptoms and signs such as asthma,cough,and phlegm,reduce airway hyperresponsiveness,inhibit chronic inflammation,and improve lung function.It can also effectively reduce recurrence and has good safety.The mechanism may be related to regulating cytokine levels,alleviating airway inflammation,improving immune function,regulating various amino acid metabolism levels,down-regulating ERK and NF-κB expressions,and increasing serum fibronectin levels.There were few experimental studies on this mechanism,which need to be strengthened in the future.

关 键 词：呼吸系统 越婢加半夏汤 临床应用 作用机制 研究进展 综述 

分 类 号：R259[医药卫生—中西医结合]