急性痘疮样苔藓样糠疹1例报道并文献复习  

A case of pityriasis lichenoides et varioliformis acuta and literature review

作　　者：管凤 赵孝琴 陈洁 GUAN Feng;ZHAO Xiaoqin;CHEN Jie(Department of Dermatology,Zhuji People's Hospital,Shaoxing,Zhejiang 311899,China)

机构地区：[1]诸暨市人民医院皮肤科,浙江绍兴311899

出　　处：《医药前沿》2025年第9期54-55,58,共3页Journal of Frontiers of Medicine

摘　　要：急性痘疮样苔藓样糠疹(PLEVA)是一种临床较为少见的炎症性皮肤病,其皮损形态多样,包括红斑、丘疹、坏死及结痂等,常伴瘙痒或疼痛,易被误诊或漏诊,且治疗比较困难。本文报道1例周身红斑、丘疹、坏死结痂伴瘙痒及疼痛的患者,通过综合其临床症状及组织病理学表现,最终明确诊断为PLEVA。在治疗上,采用托法替布、糖皮质激素、复方甘草酸苷联合光疗等多模式治疗方案,患者症状获得缓解,疗效满意。本研究旨在通过该病例的诊治经验,为临床医生提供参考,以提高对该病的认识及诊疗水平。Pityriasis lichenoides et varioliformis acuta(PLEVA)is a relatively rare inflammatory skin disease characterized by diverse skin lesions,including erythema,papules,necrosis,and crusts,often accompanied by itching or pain.It is prone to misdiagnosis or missed diagnosis and is challenging to treat.This study reported a case of a patient with generalized erythema,papules,necrotic crusts,itching,and pain.Through a comprehensive evaluation of clinical symptoms and histopathological findings,the patient was definitively diagnosed with PLEVA.The treatment regimen included tofacitinib,glucocorticoids,compound glycyrrhizin,and phototherapy,which led to symptom relief and satisfactory outcomes.This study aims to provide clinical insights and enhance the understanding and management of this condition by sharing the diagnostic and therapeutic experience of this case.

关 键 词：急性痘疮样苔藓样糠疹 托法替布 糖皮质激素 复方甘草酸苷 光疗 

分 类 号：R373[医药卫生—病原生物学]