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作 者:邹曼玉 ZOU Manyu(Department of Neonatology,The First Hospital of Anhui University of Science and Technology,Huainan,Anhui 232007,China)
机构地区:[1]安徽理工大学第一附属医院新生儿科,安徽淮南232007
出 处:《医药前沿》2025年第9期56-58,共3页Journal of Frontiers of Medicine
摘 要:新生儿完全性房室传导阻滞(Ⅲ度房室传导阻滞)的发病概率约为每15000~22000例活产婴儿中有1例。患有这种疾病的儿童预后较差,其中大多数需要起搏器治疗。本院收治的一对早产双胞胎其中1例确诊为完全性房室传导阻滞,另1例则完全正常。通过该病例的诊疗过程、病例分析和文献研究,了解了可能导致这种差异结果的病理机制。自身抗体相关性心脏传导阻滞的发生涉及多种因素,并且由于个体差异,婴儿的心脏损伤结局和预后差别很大,完全房室传导阻滞是最严重的情况,患狼疮母亲生育的新生儿出生后应完善抗SSA/Ro和抗SSB/La抗体检查,及早完善心电图、心脏彩色多普勒超声,并尽快安装起搏器。The probability of neonatal complete atrioventricular block(III degree atrioventricular block)is approximately 1 per 15000-22000 live births.Children with this disease have a poor prognosis,most of which require pacemaker therapy.One of the preterm twins admitted to the authors had a confirmed complete atrioventricular block and the other was completely normal.Through the diagnosis and treatment process,case analysis and literature study,the pathological mechanism that may lead to this differential outcome.The occurrence of ACHB involves a variety of factors,and due to individual differences,the outcome and prognosis of cardiac injury are very different.Complete atrioventricular block is the most serious case.After the birth of anti-SSA/Ro and anti-SSB/La antibodies should be improved,electrocardiogram and cardiac color ultrasound should be improved as soon as possible,and pacemaker should be installed as soon as possible.
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