基于“胃不和则卧不安”分析经皮迷走神经刺激治疗炎症性肠病共病睡眠障碍的效应机制  

Effect Mechanism Analysis of taVNS in the Treatment of Inflammatory Bowel Disease with Sleep Disorder Based on"Gastric Disharmony Causes Sleep Restlessness"

作　　者：解晓霞 张瑞环 姚震 何旭 杨正宁 陈钧 XIE Xiaoxia;ZHANG Ruihuan;YAO Zhen;HE Xu;YANG Zhengning;CHEN Jun(Shaanxi University of Chinese Medicine,Xianyang 712046,China;School of Acupuncture and Massage,Beijing University of Chinese Medicine,Beijing 102400,China;Shaanxi Provincial TCM Hospital,Xi´an 710000,China)

机构地区：[1]陕西中医药大学,陕西咸阳712046 [2]北京中医药大学针灸推拿学院,北京102400 [3]陕西省中医医院,陕西西安710000

出　　处：《西部中医药》2025年第3期23-26,共4页Western Journal of Traditional Chinese Medicine

基　　金：陕西省人才推进计划项目(2017KJXX-84)。

摘　　要：从“胃不和则卧不安”理论入手,探讨睡眠障碍与胃肠疾病相互影响的双向因果关系。认为炎症反应是炎症性肠病(inflammatory bowel disease,IBD)与睡眠障碍的共同靶点,并系统论证了皮耳迷走神经刺激治疗IBD共病失眠障碍的效应机制,以期为治疗IBD共病睡眠障碍提供更多的临床诊疗思路。On the foundation of"gastric disharmony causes sleep restlessness",the paper discusses the relationship between sleep disorder and gastrointestinal disease,both interacting as the cause and the results.Inflammation is the common target of inflammatory bowel disease(IBD)and sleep disorder,the effect mechanism of pilosebaceous vagus nerve stimulation in the treatment of IBD with sleep disorder was systematically substantiated so as to provide more ideas for clinical diagnosis and treatment for the diseases.

关 键 词：炎症性肠病 睡眠障碍 胆碱能抗炎途径 效应机制 

分 类 号：R269[医药卫生—中西医结合]