全血锌离子与小儿轮状病毒胃肠炎严重程度的关联  

Correlation Between Whole Blood Zinc Ions and the Severity of Pediatric Rotavirus Gastroenteritis

作　　者：刘慧芳 宋征征 胡艳丽 Liu Huifang;Song Zhengzheng;Hu Yanli(Pediatric Outpatient Emergency Department,Jiaozuo Maternal and Child Health Hospital,Jiaozuo,Henan,454000,China)

机构地区：[1]焦作市妇幼保健院儿科门急诊,河南焦作454000

出　　处：《黑龙江医学》2025年第5期573-576,共4页Heilongjiang Medical Journal

摘　　要：目的:分析全血锌离子与小儿轮状病毒性胃肠炎(RVGE)严重程度的关联。方法:回顾性分析2022年1月—2023年5月焦作市妇幼保健院收治的122例腹泻患儿的临床资料,归纳轮状病毒性胃肠炎发病的危险因素,分析全血锌离子(Zn^(+))与RVGE患儿病情严重程度的关联。结果:吮指习惯、有感染源接触史、白细胞(WBC)≥12×10^(9)/L、中性粒细胞(NE)≤50%、钠离子(Na^(+))>145 mmol/L、钾离子(K^(+))>5.5 mmol/L、氯离子(CI^(-))<98 mmol/L、Zn^(+)<65μmol/L为RVGE发病的危险因素。重型组的体重丢失率、大便次数、体温均高于中型组、轻型组;重型组的Zn^(+)低于中型组、轻型组,差异均有统计学意义(F=32.13、16.75、39.84、6.41,P<0.05)。Zn^(+)与RVGE患儿的脱水程度、大便次数、体温负相关(r=-0.152、-0.153、-0.151,P<0.05)。结论:检测Zn^(+)能一定程度上评估患儿病情,并指导临床治疗。Objective:To analyze the correlation between whole blood zinc ions and the severity of RVGE in children.Methods:Retrospective analysis of clinical data from 122 children with diarrhea in Jiaozuo Maternal and Child Health Hospital from January 2022 to May 2023,summarize the risk factors for the onset of rotavirus gastroenteritis,and analyze the correlation between whole blood zinc ions(Zn^(+))and the severity of RVGE in children.Results:Finger sucking habit,history of contact with infectious sources,WBC≥12×10^(9)/L,NE≤50%,Na^(+)>145 mmol/L,K^(+)>5.5mmol/L,CI^(-)<98 mmol/L,Zn^(+)<65μmol/L were the risk factors of the onset of RVGE.The weight loss rate,frequency of bowel movements,and body temperature of the heavy group were higher than those of the medium and light groups.Zn^(+)in the heavy group was lower than that in the medium and light groups(F=32.13,16.75,39.84,6.41;P<0.05).Zn^(+)was negatively correlated with the degree of dehydration,frequency of bowel movements,and body temperature in children with RVGE(r=-0.152,-0.153,-0.151;P<0.05).Conclusion:To some extent,detection of Zn^(+)can evaluate the condition of the patient and guide clinical treatment.

关 键 词：小儿轮状病毒性胃肠炎 危险因素 全血锌离子 相关性分析 临床指导 

分 类 号：R725.7[医药卫生—儿科]