根治性鼻内镜术用于嗜酸性粒细胞型慢性鼻窦炎伴鼻息肉的效果观察  

Effect of Radical Endoscopic Sinus Surgery in Eosinophilic Chronic Rhinosinusitis with Nasal Polyps

作　　者：王英凯 晁亚 忽莎楠 Wang Yingkai;Chao Ya;Hu Shanan(The Second Ward of Ear,Nose and Throat Department,Nanyang Central Hospital,Nanyang,Henan,473000,China)

机构地区：[1]南阳市中心医院耳鼻咽喉科二病区,河南南阳473000 [2]南阳市中心医院甲状腺外科,河南南阳473000

出　　处：《黑龙江医学》2025年第6期677-680,共4页Heilongjiang Medical Journal

摘　　要：目的:分析根治性鼻内镜术用于嗜酸性粒细胞型慢性鼻窦炎伴鼻息肉(EosCRSwNP)的效果及预后情况。方法:回顾性分析2022年12月—2023年12月南阳市中心医院收治的80例Eos CRSw NP患者临床资料,将接受功能性鼻内镜术治疗的39例患者作为功能治疗组,将接受根治性鼻内镜术治疗的41例患者作为根治治疗组。对比两组患者近期疗效、鼻气道阻力值、嗅觉功能、感染、复发情况以及生活质量。结果:两组患者术后近期疗效比较,差异无统计学意义(χ^(2)=3.420,P>0.05);术后1周、术后2个月,根治治疗组鼻气道阻力值均低于功能治疗组,差异均有统计学意义(t=3.354、7.112,P<0.05);术后1周、术后1个月、术后2个月,根治组嗅觉功能评分均低于功能治疗组,差异均有统计学意义(t=3.021、3.951、6.027,P<0.05);术后1周、术后1个月、术后2个月,根治组鼻内镜评分均低于功能治疗组,差异均有统计学意义(t=2.650、5.391、7.324,P<0.05);术后6个月,两组患者SNOT-22评分均较术前明显降低,差异有统计学意义(t=0.299,P<0.05);两组患者术后感染及复发情况比较,差异均无统计学意义(χ^(2)=0.833、2.066,P>0.05)。结论:根治性鼻内镜术在改善Eos CRSw NP患者的鼻气道阻力和嗅觉功能方面优于功能性鼻内镜术,且两种手术方式在近期疗效、感染和复发方面无显著差异。Objective:To analyze the effect and prognosis of radical endoscopic sinus surgery in the treatment of eosinophilic chronic rhinosinusitis with nasal polyps.Methods:A total of 80 patients with eosinophilic chronic rhinosinusitis with nasal polyps admitted to Nanyang Central Hospital from December 2022 to December 2023 were selected for retrospective analysis.39 patients who underwent functional endoscopic sinus surgery were selected as functional treatment group,and 41 patients who underwent radical endoscopic sinus surgery were selected as radical treatment group.The short-term efficacy,nasal airway resistance,olfactory function,infection,recurrence and quality of life were compared between the two groups.Results:There was no significant difference in short-term postoperative efficacy between the two groups(χ^(2)=3.420;P>0.05).1 week and 2 months after surgery,the nasal airway resistance in the radical treatment group was lower than that in the functional treatment group,with statistically significant difference(t=3.354,7.112;P<0.05).1 week,1 month and 2 months after surgery,the olfactory function scores of the radical treatment group were lower than those of the functional treatment group,with statistically significant difference(t=3.021,3.951,6.027;P<0.05).1 week,1 month and 2 months after surgery,the score of nasal endoscopy in the radical treatment group was lower than that in the functional treatment group,with statistically significant difference(t=2.650,5.391,7.324;P<0.05).6 months after surgery,SNOT-22 scores of both groups were significantly lower than those before surgery,and the difference was statistically significant(t=0.299,P<0.05).There was no significant difference in postoperative infection and recurrence between the two groups(χ^(2)=0.833,2.066;P>0.05).Conclusion:Radical endoscopic sinus surgery is superior to functional endoscopic sinus surgery in improving nasal airway resistance and olfactory function in patients with eosinophilic chronic rhinosinusitis with nasal polyps.There is no signifi

关 键 词：慢性鼻窦炎 鼻息肉 嗜酸性粒细胞型 根治性鼻内镜术 

分 类 号：R765.4[医药卫生—耳鼻咽喉科]