手术室患者麻醉深度监测与术后认知功能的相关性研究  

Correlation Study Between Anesthetic Depth Monitoring and Postoperative Cognitive Function in Operating Room Patients

作　　者：王婷婷 张静娜 王青青 代颖飞 Wang Tingting;Zhang Jingna;Wang Qingqing(Department of Surgery,People’s Hospital of Kaifeng,Kaifeng,Henan,475000,China)

机构地区：[1]开封市人民医院手术部,河南开封475000

出　　处：《黑龙江医学》2025年第6期747-749,共3页Heilongjiang Medical Journal

摘　　要：目的:探究手术室患者麻醉深度监测与术后认知功能之间的潜在联系,通过详细的统计学分析评估实验组和对照组在术后认知功能、术后并发症、麻醉药物使用和住院时间等方面的差异。方法:选取2021年1月—2023年10月开封市人民医院接受手术的12 474例全麻患者作为研究对象,随机分为对照组(n=6 237)和实验组(n=6 237)。对照组采用传统的全麻管理方法,实验组在手术前接受详细的麻醉深度监测。对比两组患者术后认知功能、术后并发症、术中麻醉药物使用及术后住院时间等情况。探究实验组患者脑电双频指数(BIS)与术后认知功能的相关性。结果:术后,实验组患者简易精神状态评价量表(MMSE)评分均高于对照组,差异均有统计学意义(t=3.21、5.12、2.78、4.56,P<0.05);实验组患者恶心、呕吐、头痛发生率均低于对照组,差异均有统计学意义(χ^(2)=18.64、14.27、11.09,P<0.05);实验组患者麻醉药物用量均少于对照组,差异均有统计学意义(t=4.32、6.18、3.91、3.02,P<0.05);实验组患者住院时间短于对照组,差异均有统计学意义(t=7.21,P<0.05)。实验组患者BIS与术后认知功能指标呈正相关,差异均有统计学意义(r=0.75、0.62、0.80、0.56,P<0.05)。结论:本研究结果表明,手术室患者中实施麻醉深度监测与术后认知功能之间存在显著关联,实验组在术后认知功能和手术相关指标上均表现出明显优势。这为进一步优化手术室患者的个体化麻醉管理提供了科学依据,有望提高手术成功率和患者的术后康复效果。Objective:To explore the potential relationship between anesthetic depth monitoring in operating room patients and postoperative cognitive function,and evaluate differences in postoperative cognitive function,postoperative complications,anesthetic drug usage,and hospital stay between the experimental and control groups through detailed statistical analysis.Methods:Selecting 12474 general anesthesia patients who underwent surgery in the department from January 2021 to October 2023,randomly assigning them to control group(n=6237)and experimental group(n=6237).The control group received the traditional general anesthesia management method,and the experimental group received detailed anesthesia depth monitoring before surgery.Postoperative cognitive function,postoperative complications,intraoperative anesthetic drug use and postoperative hospital stay were compared between the two groups.And the correlation between BIS and postoperative cognitive function in experimental group was explored.Results:After operation,MMSE scores in the experimental group were higher than those in the control group,and the difference was statistically significant(t=3.21,5.12,2.78,4.56;P<0.05).The incidence of nausea,vomiting and headache in the experimental group was significantly lower than that in the control group(χ^(2)=18.64,14.27,11.09;P<0.05).The dosage of anesthetic drugs in the experimental group was less than that in the control group,and the difference was statistically significant(t=4.32,6.18,3.91,3.02;P<0.05).The duration of hospitalization in the experimental group was shorter than that in the control group,and the difference was statistically significant(t=7.21,P<0.05).There were statistically significant differences between BIS and postoperative cognitive function indicators in the experimental group(r=0.75,0.62,0.80,0.56;P<0.05).Conclusion:The results of this study indicate a significant association between implementing anesthetic depth monitoring and postoperative cognitive function in operating room patients.The experim

关 键 词：手术室 全麻患者 麻醉深度监测 术后认知功能 术后并发症 麻醉药物使用 

分 类 号：R472.3[医药卫生—护理学]