醋酸纤维素多孔膜的制备及蛋白质吸附  

Preparation of cellulose acetate porous membrane and its adsorption for protein

作　　者：侯文杰 杨娜 任剑飞 高大海 郭改萍 戴玉华[1] HOU Wenjie;YANG Na;REN Jianfei;GAO Dahai;GUO Gaiping;DAI Yuhua(School of New Materials and Chemical Engineering,Beijing Institute of Petrochemical Technology,Beijing 102627,China)

机构地区：[1]北京石油化工学院新材料与化工学院,北京102627

出　　处：《中国塑料》2025年第3期36-40,共5页China Plastics

摘　　要：以醋酸纤维素为原料、以丙酮为溶剂、以水为非溶剂,制备结构可调、水通量高的醋酸纤维素多孔膜。并通过四甲基哌啶氧化物(TEMPO)/溴化钠(NaBr)/次氯酸钠(NaClO)氧化引入羧基基团用于蛋白质的选择分离。当醋酸纤维素浓度为10%(质量分数,下同)、凝固浴温度为10℃、非溶剂水的含量为30%时,醋酸纤维素多孔膜的综合性能最好,孔隙率为92.5%,水通量为1 655.7 L/(m^(2)·h),经氧化后,该膜在pH=6的环境下,对溶菌酶的吸附率为2 806.1 mg/g。In this study,cellulose acetate porous membranes with an adjustable structure and a high water flux were prepared by using cellulose acetate as a raw material,acetone as a solvent,and water as a non-solvent.Carboxyl groups were introduced for selective separation of protein through the oxidation of tetramethylpyridine oxide/sodium bromide/sodium hypochlorite.With a porosity of 92.5 % and a water flux of 1 655.7 L/(m~2·h),the cellulose acetate porous membranes exhibited optimal comprehensive performance at a cellulose acetate concentration of 10 wt%,a coagulation bath temperature of 10 ℃,and a non-solvent water content of 30 wt%.After oxidation,the cellulose acetate porous membrane obtained an adsorption rate of 2 806.1 mg/g for lysozyme at pH 6.

关 键 词：醋酸纤维素 非溶剂致相分离 多孔膜 

分 类 号：TQ323.721[化学工程—合成树脂塑料工业]