晚期甲状腺癌靶向治疗不良反应护理专家共识  

Expert consensus on adverse reactions of targeted therapy for advanced thyroid cancer

作　　者：中国抗癌协会甲状腺癌整合护理专业委员会 赵静 王欣 高婕 赵艺媛[3] 徐晓霞 曹家燕 马宏文[5] 金艾香[6] 赵洁 张方圆 王舒朗 陈昌连 马芳 Chinese Anti-Cancer Association Thyroid Cancer Integrated Care Committee;ZHAO Jing;WANG Xin;GAO Jie;ZHAO Yiyuan;XU Xiaoxia;CAO Jiayan;MA Hongwen;JIN Aixiang;ZHAO Jie;ZHANG Fangyuan;WANG Shulang;CHEN Changlian;MA Fang(不详;Tianjin Medical University Cancer Institute&Hospital/National Clinical Research Center for Cancer/Tianjin′s Clinical Research Center for Cancer/Key Laboratory of Cancer Prevention and Therapy,Tianjin 300060 China;Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education)/Peking University Cancer Hospital&Institute;The Affiliated Cancer Hospital of Zhengzhou University&Henan Cancer Hospital;Tianjin Union Medical Center/The First Affiliated Hospital of Nankai University;Zhejiang Provincial People′s Hospital;The Air Force Medical University,Xijing Hospital;The First Affiliated Hospital of Kunming Medical University)

机构地区：[1]不详 [2]天津医科大学肿瘤医院,国家恶性肿瘤临床医学研究中心,天津市恶性肿瘤临床医学研究中心,天津市肿瘤防治重点实验室,天津300060 [3]北京大学肿瘤医院暨北京市肿瘤防治研究所,恶性肿瘤发病机制及转化研究教育部重点实验室 [4]郑州大学附属肿瘤医院(河南省肿瘤医院) [5]天津市人民医院,南开大学第一附属医院 [6]浙江省人民医院 [7]空军军医大学西京医院 [8]昆明医科大学第一附属医院

出　　处：《护理研究》2025年第6期881-895,共15页Chinese Nursing Research

基　　金：天津市医学重点学科(专科)建设项目,编号:TJYXZDXK-011A。

摘　　要：目的:制定晚期甲状腺癌靶向治疗不良反应护理专家共识。方法:系统检索国内外数据库及相关指南网站,对相关证据进行汇总和质量评价,形成晚期甲状腺癌靶向治疗不良反应护理专家共识初稿,组织国内专家进行2轮德尔菲专家函询和1轮专家会议,结合专家临床经验对晚期甲状腺癌靶向治疗不良反应护理专家共识初稿内容进行修改并达成共识,形成晚期甲状腺癌靶向治疗不良反应护理专家共识终稿。结果:晚期甲状腺癌靶向治疗不良反应护理专家共识包括对晚期甲状腺癌靶向治疗期间出现的7种常见不良反应(皮疹、手足皮肤反应、口腔黏膜炎、腹泻、疲乏、恶心呕吐及高血压)的评估及干预。结论:晚期甲状腺癌靶向治疗不良反应护理专家共识有利于帮助护理人员对晚期甲状腺癌病人的靶向治疗不良反应进行评估及干预。Objective:To establish an expert consensus on adverse reactions of targeted therapy for advanced thyroid cancer.Methods:Chinese and international foreign databases and relevant guideline websites were retrieved.Relevant evidence was summarized and the quality of evidence was evaluated.The initial draft of expert consensus on adverse reactions of targeted therapy for advanced thyroid cancer was formed.China experts were organized to conduct two rounds of Delphi expert inquiry and one round of expert meeting.Based on the clinical experience of experts,the initial draft of expert consensus on adverse reactions of targeted therapy for advanced thyroid cancer was revised,and the experts had reached consensus.Then,the final expert consensus on adverse reactions of targeted therapy for advanced thyroid cancer was formed.Results:The evaluation and intervention of 7 common adverse reactions(rash,hand-foot skin reaction,oral mucosal inflammation,diarrhea,fatigue,nausea and vomiting,and hypertension)were included in the expert consensus on adverse reactions of targeted therapy for advanced thyroid cancer.Conclusions:The expert consensus on adverse reactions of targeted therapy for advanced thyroid cancer provides guidance for helping nursing staff evaluate and intervene in the adverse reactions of targeted therapy in patients with advanced thyroid cancer.

关 键 词：甲状腺癌 靶向治疗 不良反应 护理 专家共识 

分 类 号：R473.73[医药卫生—护理学]