电子支气管镜肺泡灌洗治疗大叶性肺炎实变期患儿的临床可行性分析  

Analysis of the Clinical Feasibility of Electron Bronchoscopic Alveolar Lavage in the Treatment of Children with Lobar Pneumonia in the Solid Phase

作　　者：聂莹 Nie Ying(Department of Pediatrics,Anyang Maternal and Child Health Hospital,Anyang,Henan 455000,China)

机构地区：[1]安阳市妇幼保健院儿科,河南安阳455000

出　　处：《哈尔滨医药》2025年第1期34-37,共4页Harbin Medical Journal

摘　　要：目的探究电子支气管镜肺泡灌洗治疗大叶性肺炎实变期患儿的可行性。方法随机选取收治的大叶性肺炎实变期患儿68例作为研究对象,按照数字表法随机分成两组,其中常规组接受常规药物治疗,电子支气管镜组接受电子支气管镜肺泡灌洗治疗,比较两组的疗效、发热时间、咳嗽时间及症状恢复时间;比较两组的炎症指标、免疫功能指标变化。结果电子支气管镜组的疗效高于常规组(P<0.05);电子支气管镜组发热时间、咳嗽时间、体温恢复时间、肺部啰音消失时间均低于常规组(P<0.05);两组治疗后的IL-6、CRP均低于治疗前,并且电子支气管镜组低于常规组(P<0.05);两组治疗后的CD4^(+)、CD4^(+)/CD8^(+)均高于治疗前,并且电子支气管镜组高于常规组(P<0.05)。结论对于大叶性肺炎实变期患儿,采取电子支气管镜肺泡灌洗治疗能够有效减轻症状,降低炎症反应,促进免疫功能恢复,具备较好的疗效。Objective To investigate the feasibility of electron bronchoscopic alveolar lavage for the treatment of children with lobar pneumonia in the solid stage.Methods Selected 68 cases of lobar pneumonia in the solid stage of children as the research object,according to the numerical table method randomly divided into two groups,in which the conventional group to receive conventional drug therapy,electronic bronchoscopy group to receive electronic bronchoscopy alveolar lavage treatment,compare the efficacy of the two groups,fever time,cough time,temperature recovery time,the disappearance of the lung rales time.Comparison of inflammatory indexes and immune function indexes between the two groups.Results The efficacy of the electronic bronchoscopy group was higher than that of the conventional group(P<0.05);the fever time,cough time,temperature recovery time,and the disa-ppearance time of lung rales in the electronic bronchoscopy group was shorter than in the conventional group(P<0.05).Levels of IL-6 and CRP decreased in both groups after treatment,with greater reductions observed in the electronic bronchoscopy group compared to the conventional group(P<0.05).Additionally,CD4^(+)and CD4^(+)/CD8^(+)ratios were lower in the electronic bronchoscopy group than in the conventional group.Both groups showed reductions in CD4^(+)/CD8^(+)ratios compared to their initial values,with the electronic bronchoscopy group demonstrating a more significant improvement.Furthermore,the CD4^(+)and CD4^(+)/CD8^(+)ratios were higher post-treatment than before treatment in both groups,and the electronic bronchoscopy group was higher than the conventional group(P<0.05).Conclusion For children with lobar pneumonia in the solid stage,bronchoscopic alveolar lavage can effectively reduce symptoms,lower inflammatory response,promote the recovery of immune function,and has better efficacy.

关 键 词：电子支气管镜 支气管肺泡灌洗 大叶性肺炎 肺实变 

分 类 号：R720.5[医药卫生—儿科]