近红外荧光介导多模态成像在宫颈癌临床前基础研究中的应用  

Application of near-infrared fluorescence mediated multimodal imaging in preclinical basic research on cervical cancer

作　　者：杜仲 朱丽君 熊加宝 高宇翔 努尔尼沙·阿力甫 DU Zhong;ZHU Lijun;XIONG Jiabao;GAO Yuxiang;NURNISHA Alifu(The Second Affiliated Hospital of Xinjiang Medical University,Urumqi 830063,China;State Key Laboratory of Pathogenesis,Prevention and Treatment of High Incidence Diseases in Central Asia/School of Medical Engineering and Technology,Xinjiang Medical University,Urumqi 830054,China)

机构地区：[1]新疆医科大学第二附属医院,新疆乌鲁木齐830063 [2]新疆医科大学医学工程与技术学院/新疆维吾尔自治区省部共建中亚高发病成因与防治国家重点实验室,新疆乌鲁木齐830054

出　　处：《中国医学物理学杂志》2025年第3期324-327,共4页Chinese Journal of Medical Physics

基　　金：国家自然科学基金(82060326,62035011)。

摘　　要：医学影像技术在宫颈癌的诊断及预后评估方面发挥重要作用。随着影像技术的快速发展,多模态成像结合多种成像技术的优势以获得更全面、更准确的诊断信息来实现精准诊疗,为宫颈癌的诊断提供新的成像方式。同时近红外荧光成像以高灵敏度和低侵入性的优势在多模态成像中占据重要地位。本文从近红外荧光介导多模态成像的探针出发,总结了近红外荧光成像结合核磁成像、计算机断层扫描成像以及光声成像等不同影像技术的多模态成像方式在宫颈癌临床前基础研究领域的应用以及对未来的展望。Medical imaging technology is essential for the diagnosis and prognostic evaluation of cervical cancer.With the rapid development of imaging technology,multimodal imaging which combines the advantages of various imaging techniques to obtain more comprehensive and accurate diagnostic information for precise diagnosis and treatment is served as a new imaging method for the diagnosis of cervical cancer.Meanwhile,near-infrared fluorescence imaging occupies an important position in multimodal imaging for its advantages of high sensitivity and low invasiveness.Starting from the probe of near-infrared fluorescence mediated multimodal imaging,the study explores the applications and future prospects of multimodal imaging methods combining near-infrared fluorescence imaging with different imaging techniques such as magnetic resonance imaging,computed tomography and photoacoustic imaging in the preclinical basic research on cervical cancer.

关 键 词：近红外荧光成像 宫颈癌 多模态成像 影像技术 综述 

分 类 号：R318[医药卫生—生物医学工程] R35[医药卫生—基础医学]