某医院215例药品不良反应报告分析  

215 Cases of Adverse Drug Reactions in a Hospital

作　　者：郑久明 崔盛 ZHENG Jiu-ming;CUI Sheng(Ningbo Taikang Hospital,Ningbo 315100,China;Mingzhou Hospital of Zhejiang University,Ningbo 315100,China)

机构地区：[1]宁波泰康脑科医院,浙江宁波315100 [2]浙江大学明州医院,浙江宁波315100

出　　处：《解放军药学学报》2025年第1期78-81,共4页Pharmaceutical Journal of Chinese People's Liberation Army

摘　　要：目的分析某医院215例药品不良反应(ADR)报告发生规律及特点,为该院临床合理用药提供参考。方法采用回顾性分析方法,对该院2020年1月1日-2022年3月31日的215例ADR报告进行分析,重点分析ADR上报例数的科室、引起ADR的疑似药品种类、使用途径以及累及系统-器官和临床表现等。结果数据显示215例ADR报告中,其中34.42%是由药师填写,约1/2临床科室未上报。215例ADR报告共涉及疑似药品258例次,占据首位的是抗感染药(84例次,32.56%)。258例次疑似药品中给药途径最多的是静脉注射(182例,70.54%)。ADR累积系统-器官排名首位的是皮肤及其附件,最常见的临床症状是皮疹和瘙痒。结论积极上报ADR并对ADR报告进行分析,对该院临床合理用药具有重要指导作用。Objective To anlayze the characteristics of 215 cases of adverse drug reactions(ADRs)in a hospital in order to provide a reference for clinical rational drug use.Methods Case reports of 215 ADRs collected from the pharmacy department of our hospital from January 1,2020 to March 31,2022 were retrospectively analyzed in terms of the ranking of departments responsible,types of suspected drugs,routes of use,systems-organs involved and clinical manifestations.Results The data showed that 34.42%of the ADRs were reported by pharmacists,but nearly half of the clinical departments reported none.These reports involved 258 suspected drugs,with anti-infective drugs(84 cases,32.56%)ranking first.Among the 258 suspected drugs,intravenous injection was the most common route of administration(182 cases,70.54%).At the top of the list of organs involved was the skin and its appendages,with rash and itching as the most common clinical manifestations.Conclusion Reporting and analyzing ADRs quickly can facilitate clinical rational drug use in a hospital.

关 键 词：药品不良反应 抗感染药 皮疹 合理用药 

分 类 号：R969[医药卫生—药理学]