中老年人肌少症性肥胖与慢性肺病关系研究  

Study on the relationship between sarcopenic obesity and chronic lung disease in middle-aged and elderly people

作　　者：赵春 刘园 ZHAO Chun;LIU Yuan(Department of Respiratory and Critical Care Medicine,The First Affiliated Hospital of China Medical University,Shenyang 110001,China;Department of Neurosurgery,The First Affiliated Hospital of China Medical University,Shenyang 110001,China)

机构地区：[1]中国医科大学附属第一医院呼吸与危重症医学科,沈阳110001 [2]中国医科大学附属第一医院神经外科,沈阳110001

出　　处：《医学新知》2025年第3期256-261,共6页New Medicine

摘　　要：目的探讨中老年人肌少症性肥胖(sarcopenic obesity,SO)与慢性肺病的关系。方法利用中国健康与养老追踪调查(CHARLS)数据,选取2011年、2015年、2018年和2020年四次调查数据,纳入基线调查时年龄≥45岁的中老年人作为研究对象。通过Cox比例风险回归模型分析SO与慢性肺病发病风险的关系。结果纳入8720名研究对象,9年随访期间共1053人(12.08%)新发慢性肺病,其中正常组、仅肌少症组、仅肥胖组、SO组慢性肺病的发病率分别为10.84%、13.55%、9.96%和18.47%。与正常组相比,仅肌少症组和SO组发生慢性肺病的风险分别增加了17%[HR=1.17,95%CI(1.01,1.34)]和86%[HR=1.86,95%CI(1.41,2.46)]。结论SO显著增加了中老年人慢性肺病的发生风险,提示中老年人应加强锻炼,保持健康体重以提高生活水平。Objective To explore the relationship between sarcopenic obesity(SO)and chronic lung disease in middle-aged and elderly people.Methods Using data from the China Health and Retirement Longitudinal Study(CHARLS),four surveys were selected in 2011,2015,2018,and 2020,and middle-aged and elderly people aged≥45 years at the time of the baseline survey were included as study subjects.The relationship between SO and the risk of developing chronic lung disease was analyzed by Cox proportional risk regression model.Results A total of 8,720 study subjects were included,and a total of 1,053(12.08%)developed new chronic lung disease during the 9-year follow-up period,with the prevalence of chronic lung disease in the normal,sarcopenia-only,obesity-only,and SO groups being 10.84%,13.55%,9.96%,and 18.47%,respectively.Compared with the normal group,the risk of chronic lung disease was increased by 17%[HR=1.17,95%CI(1.01,1.34)]and 86%[HR=1.86,95%CI(1.41,2.46)]in the sarcopenia-only group and SO group,respectively.Conclusion SO significantly increased the risk of chronic lung disease in middle-aged and older adults,suggesting that middle-aged and older adults should increase exercise and maintain a healthy weight to improve their standard of living.

关 键 词：肌少症 肌少症性肥胖 慢性肺病 中老年人 

分 类 号：R563.9[医药卫生—呼吸系统] R746.2[医药卫生—内科学]