Clinical impact of drug-coated balloon treatment of coronary artery disease in elderly patients  

作　　者：Eun-Seok SHIN Mi Hee JANG Sunwon KIM Dong Oh KANG Ki-Bum WON Bitna KIM Ae-Young HER 

机构地区：[1]Department of Cardiology,Ulsan University Hospital,University of Ulsan College of Medicine,Ulsan,South Korea [2]Cardiovascular Center,Department of Internal Medicine,Korea University Ansan Hospital,Korea University College of Medicine,Ansan,South Korea [3]Cardiovascular Center,Department of Internal Medicine,Korea University Guro Hospital,Korea University College of Medicine,Seoul,South Korea [4]Division of Cardiology,Chung-Ang University Gwangmyeong Hospital,Gwangmyeong,Gyeong,South Korea [5]Division of Cardiology,Department of Internal Medicine,Kangwon National University College of Medicine,Kangwon National University School of Medicine,Chuncheon,South Korea

出　　处：《Journal of Geriatric Cardiology》2025年第1期150-158,共9页老年心脏病学杂志(英文版)

摘　　要：Background Data on drug-coated balloon(DCB)treatment in elderly patients are limited.This study was to evaluate the efficacy of DCB treatment in percutaneous coronary intervention(PCI)among elderly patients.Methods A retrospective analysis included 232 patients aged 75 years or older with coronary artery disease who underwent successful PCI using either DCB alone or in combination with drug-eluting stent(DES)based on pre-dilation results(DCB-based PCI).These patients were compared with 1818 elderly patients who underwent second-generation DES implantation(DES-only PCI).The endpoint was major adverse cardiovascular events(MACE)at 2-year follow-up.Results In the DCB-based PCI,61.2%of patients received DCB-only treatment.Compared to DES-only PCI,the DCB-based PCI group had fewer stents(0.5±0.7 and 1.7±0.8,P<0.001),shorter stent lengths(13.3±20.9 mm and 37.4±23.0 mm,P<0.001),and lower usage of small stents with a diameter of 2.5 mm or less(15.6%and 28.7%,P=0.010).The DCB-based PCI group exhibited lower rate of MACE(5.5%and 13.1%,P=0.003),target vessel revascularization(1.1%and 5.6%,P=0.017)and major bleeding(0.7%and 5.1%,P=0.009)at 2-year follow-up.The reduced risk in 2-year MACE was consistently observed across various matching procedures,with the most significant reduction noted in target vessel revascularization and major bleeding.Conclusion The DCB-based PCI reduced stent burden,particularly in the usage of small diameter stents,and was associated with lower risks of MACE,target vessel revascularization,and major bleeding compared to DES-only PCI in elderly patients.

关 键 词：patients BALLOON CORONARY 

分 类 号：R54[医药卫生—心血管疾病]