中国肝移植受者肌肉减少症临床诊疗指南  

Chinese clinical guideline for the diagnosis and treatment of sarcopenia in liver transplant recipients

作　　者：中华医学会器官移植学分会肝移植学组 中国医师协会器官移植医师分会 徐骁 鲁迪[1] 卓建勇 林祖源 杭化莲 刘治坤 范广晗 庄莉 沈恬 朱恒凯 Liver Transplantation Group,Branch of Organ Transplantation of Chinese Medical Association;Branch of Organ Transplant Physicians of Chinese Medical Doctor Association;Xu Xiao(不详;Hangzhou Medical College,Hangzhou 311300,China;Institute of Translational Medicine,Zhejiang University,Hangzhou 310058,China)

机构地区：[1]不详 [2]杭州医学院,杭州311300 [3]浙江大学转化医学研究院,杭州310058

出　　处：《中华移植杂志(电子版)》2024年第6期355-365,共11页Chinese Journal of Transplantation(Electronic Edition)

基　　金：国家重点研发计划(2021YFA1100500);国家自然科学基金重大研究计划(92159202);浙江省“尖兵领雁+X”研发攻关计划(2024C03051)。

摘　　要：肌肉减少症(以下简称肌少症)是一组由多种病因导致的以肌肉量减少和肌肉功能减退为特征的全身性、进行性骨骼肌疾病。我国肝移植受者肌少症的发生率超40%,严重制约移植疗效。为规范和优化肝移植相关肌少症的诊疗和管理,中华医学会器官移植学分会肝移植学组和中国医师协会器官移植医师分会组织专家研讨,结合循证医学依据和我国临床实践经验,并充分借鉴相关国内外文献,制订《中国肝移植受者肌肉减少症临床诊疗指南》。本指南重点阐述肝移植相关肌少症诊断评估、临床防治等内容,并科学规范地提出系列推荐意见,旨在优化我国肝移植围手术期乃至中长期健康管理。Sarcopenia is a group of systemic,progressive skeletal muscle diseases characterized by decreased muscle mass and muscle function due to a variety of etiological factors.The incidence of sarcopenia in liver transplant recipients in China exceeds 40%,which seriously restricts the efficacy of liver transplantation.To standardize and optimize the diagnosis and management of sarcopenia associated with liver transplantation,the Liver Transplantation Group,Branch of Organ Transplantation of Chinese Medical Association;Branch of Organ Transplant Physicians of Chinese Medical Doctor Association have organized experts to summarize and discuss the clinical diagnosis and management of sarcopenia associated with liver transplantation in China by combining the evidence-based medical basis and China's clinical practice experience,and by drawing on the relevant domestic and international literature.This guideline focuses on the diagnosis,assessment,clinical prevention and treatment of sarcopenia related to liver transplantation,and puts forward a series of recommendations in a scientific and standardized way,aiming at optimizing the perioperative and even mid-and long-term health management of liver transplantation in China.

关 键 词：肝移植 肌肉减少症 骨骼肌质量 围手术期管理 

分 类 号：R65[医药卫生—外科学]