广东省某铀矿周围男性居民代谢不健康状态现况及其影响因素  

Metabolically unhealthy status and its influencing factors of male residents around a uranium mine in Guangdong Province

作　　者：李慧娴 陈慧峰[1] 陈铿铿[1] 黄伟旭[1] 邹剑明[1,2] LI Huixian;CHEN Huifeng;CHEN Kengkeng;HUANG Weixu;ZOU Jianming(Guangdong Province Hospital for Occupational Disease Prevention and Treatment,Guangzhou,Guangdong 510300,China;不详)

机构地区：[1]广东省职业病防治院,广东广州510300 [2]中山大学公共卫生学院,广东广州510080

出　　处：《中国职业医学》2024年第6期638-644,共7页China Occupational Medicine

基　　金：广东省基础与应用基础研究基金(2019A1515011969,2022A1515012421,2023A1515010414)。

摘　　要：目的探讨广东省某铀矿周围男性居民代谢不健康状态(MUS)现况及其影响因素。方法采用二阶段随机抽样方法,选择出生并长期居住于广东省某铀矿周围的867名男性居民为研究对象;以铀矿为中心,按居住距离<10和10~20 km半径范围分为10 km组和20 km组,检测其血压、空腹血糖和血脂等指标。采用多因素logistic回归分析MUS及其各组分影响因素。结果研究对象MUS检出率为42.2%;MUS组分舒张压、收缩压、空腹血糖、三酰甘油偏高和高密度脂蛋白胆固醇(HDL-C)偏低检出率分别为48.8%、60.9%、11.9%、40.7%和19.3%。10 km组人群MUS检出率低于20 km组(38.5%vs 45.9%,P<0.05)。多因素logistic回归分析结果显示,年龄>50岁组人群检出MUS和收缩压偏高的风险高于年龄≤50岁者(P值均<0.05);饮酒人群检出MUS、收缩压偏高、舒张压偏高、三酰甘油偏高和HDL-C偏低的风险均高于不饮酒者(P值均<0.05);偶尔食用水果组人群检出MUS的风险高于经常食用水果者(P<0.05);超重与肥胖组人群检出MUS、收缩压偏高、舒张压偏高、三酰甘油偏高、HDL-C偏低的风险均高于体质量正常者(P值均<0.05);20 km组人群检出MUS和HDL-C偏低的风险高于10 km组(P值均<0.05)。结论年龄>50岁、饮酒、偶尔食用水果、超重与肥胖均为铀矿周围男性居民检出MUS的危险因素,年龄>50岁、饮酒、超重与肥胖可不同程度影响MUS各组分水平的检出。尚未观察到环境辐射水平是本组研究对象检出MUS的危险因素。Objective To investigate the status of metabolically unhealthy status(MUS)and its influencing factors in male residents living around a uranium mine in Guangdong Province.Methods A total of 867 local male residents born and living around a uranium mine in Guangdong Province were selected as the study subjects using two-stage random sampling method.The residents were divided into 10 km-and 20 km-radius groups,according to their living distance<10 km or 10-20 km from the uranium mine.Blood pressure,fasting blood glucose,and blood lipid levels were tested among the study subjects.The influencing factors of MUS and its components were analyzed by multiple logistic regression.Results The detection rate of MUS was 42.2%.The detection rates of MUS component such as elevated diastolic blood pressure,elevated systolic blood pressure,elevated fasting blood glucose,elevated triglyceride and low high-density lipoprotein cholesterol(HDL-C)were 48.8%,60.9%,11.9%,40.7%and 19.3%,respectively.The MUS detection rate in the 10 km group was lower than that in the 20 km group(38.5%vs 45.9%,P<0.05).The result of multivariate logistic regression analysis showed that subjects aged>50 years had a higher risk of MUS and elevated systolic blood pressure than those aged≤50 years(all P<0.05).Drinkers had a higher risk of MUS,elevated systolic blood pressure,elevated diastolic blood pressure,elevated triglyceride,and low HDL-C than non-drinkers(all P<0.05).Those who ate fruit occasionally had a higher risk of MUS than those who ate fruit regularly(P<0.05).Overweight and obese individuals had a higher risk of MUS,elevated systolic blood pressure,elevated diastolic blood pressure,elevated triglyceride,and low HDL-C than those with normal body mass(all P<0.05).Individuals in the 20 km group had a higher risk of MUS and low HDL-C than the 10 km group(all P<0.05).Conclusion The risk factors of MUS detection among male residents living around the uranium mines are age>50 years,drinking,occasional fruit intake,and being overweight or obese.Age>50

关 键 词：铀矿 代谢不健康状态 血压 空腹血糖 血脂 现况调查 影响因素 

分 类 号：R144[医药卫生—公共卫生与预防医学]