气道正压通气在妊娠期阻塞性睡眠呼吸暂停中的应用进展  

Review of positive airway pressure in the treatment of pregnancy with obstructive sleep apnea syndrome

作　　者：刘欣然 王晶玉 韩芳[2] 刘国莉[3] LIU Xinran;WANG Jingyu;HAN Fang;LIU Guoli(Nursing School of Peking University,Beijing 100191,China;Department of Respiratory and Sleep Medicine,Peking University People’s Hospital,Beijing 100044,China;Department of Obstetrics and Gynecology,Peking University People’s Hospital,Beijing 100044,China)

机构地区：[1]北京大学护理学院,北京100191 [2]北京大学人民医院呼吸睡眠医学科,北京100044 [3]北京大学人民医院妇产科,北京100044

出　　处：《新医学》2025年第2期215-221,共7页Journal of New Medicine

基　　金：北京市自然科学基金(京津冀基础研究合作专项)(22JCZXJC00160)。

摘　　要：阻塞性睡眠呼吸暂停(OSA)在妊娠期患病率高,是妊娠期高血压、子痫前期和妊娠期糖尿病的独立危险因素,同时易导致新生儿早产、低出生体质量等多种不良妊娠结局。及时治疗对改善妊娠期OSA症状甚至逆转不良妊娠结局有着重要的作用。气道正压通气(PAP)是治疗OSA的首选方法,其在妊娠期患者中的应用也日益受到关注。文章对PAP治疗妊娠期OSA的现状进行综述,详细探讨了PAP对改善妊娠期OSA症状、控制妊娠期高血压、高血糖的进展及改善机体生物学标志物等的积极影响。以期提高临床工作者对妊娠期OSA诊治的重视程度,为临床治疗提供参考。Obstructive sleep apnea(OSA)exhibits a high prevalence during pregnancy and serves as an independent risk factor for hypertensive disorders during pregnancy,preeclampsia,and gestational diabetes mellitus.Moreover,it readily leads to various adverse pregnancy outcomes,such as preterm birth and low birth weight.Timely treatment plays a crucial role in improving OSA during pregnancy and may even reverse adverse pregnancy outcomes.Positive airway pressure(PAP)is the preferred treatment for OSA,and its application in pregnant patients is increasingly receiving attention.This review provides a comprehensive review of the current status of positive airway pressure(PAP)therapy for obstructive sleep apnea(OSA)during pregnancy,delving into the positive impacts of PAP on alleviating OSA symptoms during pregnancy,controlling the progression of gestational hypertension and hyperglycemia,and improving biomarkers in the body.The aim is to enhance the awareness of clinical practitioners towards the diagnosis and treatment of OSA during pregnancy and to provide reference for clinical treatment.

关 键 词：气道正压通气 阻塞性睡眠呼吸暂停 妊娠期高血压疾病 妊娠期糖尿病 妊娠结局 

分 类 号：R71[医药卫生—妇产科学]