脑出血患者血肿穿刺引流术后颅内感染危险因素分析  

Analysis of Risk Factors for Intracranial Infection in Patients with Cerebral Hemorrhage after Hematoma Puncture and Drainage

作　　者：郭校 Guo Xiao(Department of Neurosurgery,Wuxue Hospital of Traditional Chinese Medicine,Wuxue 435400,Hubei Province,China)

机构地区：[1]武穴市中医医院神经外科,湖北武穴435400

出　　处：《中外医药研究》2025年第6期9-11,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:分析脑出血患者血肿穿刺引流术后发生颅内感染的危险因素。方法:选取2021年11月-2022年11月武穴市中医医院收治的已接受血肿穿刺引流术治疗的100例脑出血患者为研究对象,按照术后是否发生颅内感染分为感染组(n=32)和未感染组(n=68),结合临床资料及相关文献资料筛选出可能与颅内感染有关的危险因素进行对比分析,采用多因素Logistic回归模型分析独立危险因素。结果:感染组与未感染组年龄、术后发生脑脊液渗漏、注射尿激酶次数、置管与脑室是否相通、术前血清蛋白水平比较,差异有统计学意义(P<0.05);多因素Logistic回归模型分析结果显示,年龄≥60岁、术前血清蛋白水平<35 g/L是脑出血患者血肿穿刺引流术后发生颅内感染的独立危险因素(P<0.05)。结论:高龄、术前血清蛋白水平<35 g/L是脑出血患者血肿穿刺引流术后发生颅内感染的危险因素,需结合其年龄及营养状况,制定针对性的防控方案。Objective:To analyze the risk factors for intracranial infection in patients with cerebral hemorrhage after hematoma puncture and drainage.Methods:A total of 100 patients with cerebral hemorrhage who underwent hematoma puncture and drainage at Wuxue Hospital of Traditional Chinese Medicine from November 2021 to November 2022 were selected as the study subjects.The patients were divided into an infection group(n=32)and a non-infection group(n=68)based on the occurrence of postoperative intracranial infection.Clinical data and relevant literature were used to identify potential risk factors for intracranial infection,which were then compared and analyzed.Multivariate logistic regression analysis was performed to identify independent risk factors.Results:Significant differences were observed between the infection and non-infection groups in terms of age,postoperative cerebrospinal fluid leakage,number of urokinase injections,catheter-ventricle communication,and preoperative serum protein level(P<0.05).Multivariate logistic regression analysis revealed that age≥60 years and preoperative serum protein level<35 g/L were independent risk factors for intracranial infection after hematoma puncture and drainage in patients with cerebral hemorrhage(P<0.05).Conclusion:Advanced age and preoperative serum protein level<35 g/L are risk factors for intracranial infection in patients with cerebral hemorrhage after hematoma puncture and drainage.Targeted prevention and control strategies should be developed based on the patient's age and nutritional status.

关 键 词：脑出血 血肿穿刺引流术 颅内感染 危险因素 

分 类 号：R651.1[医药卫生—外科学]