Cortical Morphological Networks Difer Between Gyri and Sulci  

作　　者：Qingchun Lin Suhui Jin Guole Yin Junle Li Umer Asgher Shijun Qiu Jinhui Wang 

机构地区：[1]Institute for Brain Research and Rehabilitation,South China Normal University,Guangzhou 510631,China [2]Department of Air Transport,Faculty of Transportation Sciences,Czech Technical University in Prague(CTU),Prague 12800,Czech Republic [3]School of Interdisciplinary Engineering and Sciences(SINES),National University of Science and Technology(NUST),Islamabad 44000,Pakistan [4]Department of Radiology,The First Afliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510405,China [5]Key Laboratory of Brain,Cognition and Education Sciences,Ministry of Education,Guangzhou 510631,China [6]Center for Studies of Psychological Application,South China Normal University,Guangzhou 510631,China [7]Guangdong Key Laboratory of Mental Health and Cognitive Science,South China Normal University,Guangzhou 510631,China

出　　处：《Neuroscience Bulletin》2025年第1期46-60,共15页神经科学通报(英文版)

基　　金：supported by the STI 2030-Major Projects(2021ZD0200500);the National Social Science Foundation of China(20&ZD296);Key Realm R&D Program of Guangdong Province(2019B030335001).

摘　　要：This study explored how the human cortical folding pattern composed of convex gyri and concave sulci afected single-subject morphological brain networks,which are becoming an important method for studying the human brain connectome.We found that gyri-gyri networks exhibited higher morphological similarity,lower small-world parameters,and lower long-term test-retest reliability than sulci-sulci networks for cortical thickness-and gyrifcation index-based networks,while opposite patterns were observed for fractal dimension-based networks.Further behavioral association analysis revealed that gyri-gyri networks and connections between gyral and sulcal regions signifcantly explained inter-individual variance in Cognition and Motor domains for fractal dimension-and sulcal depth-based networks.Finally,the clinical application showed that only sulci-sulci networks exhibited morphological similarity reductions in major depressive disorder for cortical thickness-,fractal dimension-,and gyrifcation index-based networks.Taken together,these fndings provide novel insights into the constraint of the cortical folding pattern to the network organization of the human brain.

关 键 词：Morphological connectivity Magnetic resonance imaging Test-retest reliability Cortical folding Graph theory 

分 类 号：TN9[电子电信—信息与通信工程]