Three-dimensional Heterogeneity and Intrinsic Plasticity of the Projection from the Cerebellar Interposed Nucleus to the Ventral Tegmental Area  

作　　者：Chen Wang Si-Yu Wang Kuang-Yi Ma Zhao-Xiang Wang Fang-Xiao Xu Zhi-Ying Wu Yan Gu Wei Chen Ying Shen Li-Da Su Lin Zhou 

机构地区：[1]Department of Physiology and Department of Psychiatry of Sir Run Run Shaw Hospital,Zhejiang University School of Medicine,Hangzhou,310016,China [2]Zhejiang Lab,Hangzhou,311500,China [3]Department of Neurology and Research Center of Neurology,Second Affiliated Hospital,Hangzhou,310009,China [4]Neuroscience Care Unit,Key Laboratory of Multiple Organ Failure of Ministry of Education,The Second Affiliated Hospital of Zhejiang University School of Medicine,Hangzhou,310009,China [5]Center for Brain Health,the Fourth Affiliated Hospital of School of Medicine,and International School of Medicine,International Institutes of Medicine,Zhejiang University,Yiwu,322000,China [6]Center of Stem Cell and Regenerative Medicine,Zhejiang University School of Medicine,Hangzhou,310058,China [7]Key Laboratory of the Diagnosis and Treatment of Severe Trauma and Burn of Zhejiang Province,Hangzhou,310009,China [8]Key Laboratory of Medical Neurobiology of Zhejiang Province,Zhejiang University School of Medicine,Hangzhou,310009,China

出　　处：《Neuroscience Bulletin》2025年第1期159-164,共6页神经科学通报(英文版)

基　　金：supported by grants from the STI2030-Major Projects(2021ZD0204000);the Key Strategic Science and Technology Cooperation Project(2023YFE0206800);the Ministry of Science and Technology of China,the National Natural Science Foundation of China(31820103005,32170976,32100791,and 81971874),Zhejiang Province Natural Science Foundation of China(LZ24C090003 and LY21C090003);the Peak Discipline Cultivation Program of Zhejiang University School of Basic Medicine.

摘　　要：Dear Editor,In recent years,there has been an increasing focus on the non-motor functions of the cerebellum[1,2].Clinical observations have demonstrated that individuals with cerebellar damage exhibit affective insensitivity,executive dysfunction,spatial cognitive impairment,personality changes,and speech difficulties,collectively known as cerebellar cognitive affective syndrome[3].Furthermore,cerebellar dysfunction has been implicated in various neurological disorders such as autism spectrum disorder,obsessive-compulsive disorder,and attention-deficit/hyperactivity disorder[4].

关 键 词：attention COLLECTIVE damage 

分 类 号：Q42[生物学—神经生物学]