肝移植术后缺血性胆道病变诊断与治疗中国实践指南  

Chinese practice guidelines for diagnosis and treatment of ischemic-type biliary lesion after liver transplantation

作　　者：中华医学会器官移植学分会 张英才[2] 冯啸[2] 李征然[2] 任杰[2] 王劲[2] 郑丰平[2] 陈文捷[2] 张琪[2] 徐骁[3] 杨扬[2] Branch of Organ Transplantation of Chinese Medical Association;Xu Xiao;Yang Yang(The Third Affiliated Hospital of Sun Yat-sen University,Guangzhou 510630,China;不详)

机构地区：[1]不详 [2]中山大学附属第三医院,广州510630 [3]浙江大学医学院附属第一医院

出　　处：《中华肝脏外科手术学电子杂志》2024年第6期739-748,共10页Chinese Journal of Hepatic Surgery(Electronic Edition)

基　　金：国家自然科学基金面上项目(82270689);中山大学附属第三医院重大人才培育计划(P02452);广州市科技计划市校(院)企业联合资助项目(2024A03J0273);广州地区临床高新、重大、特色技术(2023P-GX05)

摘　　要：我国肝脏移植历经多年的探索发展,其技术及预后已得到显著提高,术后并发症发生率也随之降低,但缺血性胆道病变仍是一个不容忽视的问题。中山大学附属第三医院于2015年制订并发表《中国内地地区肝移植后缺血性胆道病变诊断及治疗专家共识》,现结合现阶段情况及文献报道进行更新并形成指南。本指南从缺血性胆道病变的定义、发生率、发病机制、诊断、高危因素的预防以及治疗等方面进行详细阐述,旨在为肝移植术后缺血性胆道病变的诊断与治疗提供标准化、规范化的指导,以降低再移植率和病死率,提高肝移植受者的整体生存质量。Over the years of exploration and development,the surgical techniques and prognosis of liver transplantation in China have been significantly improved,resulting in a notable decrease in the prevalence of postoperative complications.However,ischemic-type biliary lesion remain a non-negligible issue.The Third Affiliated Hospital of Sun Yat-sen University formulated and published the"Expert Consensus on the Diagnosis and Treatment of Ischemic-Type Biliary Lesions after Liver Transplantation in China's mainland"in 2015,which has now been updated into aguideline based on current conditions and literature reports.This guideline elaborates in detail on the definition,incidence,pathogenesis,diagnosis,prevention of high-risk factors,and treatment of ischemic-type biliary lesion,aiming to providestandardized and normative guidance for the diagnosis and treatment of ischemic-type biliary lesion after liver transplantation,thereby reducing the rate of re-transplantation and fatality,and to improve the overall quality of life of liver transplant recipients.

关 键 词：肝移植 缺血性胆道病变 诊断 治疗 脑死亡器官捐献 边缘供肝 免疫抑制 感染 

分 类 号：R657.3[医药卫生—外科学]