肝切除术中剩余肝再生能力的评估与预测  

Evaluation and prediction of residual liver regeneration ability for hepatectomy

作　　者：吴雪云 胡小军 范应方[1,2] Wu Xueyun;Hu Xiaojun;Fan Yingfang(Department of Hepatobiliary Surgery,Zhujiang Hospital,Southern Medical University,Guangzhou 510260,China;Department of Hepatobiliary Surgery,the Third Affiliated Hospital of Southern Medical University,Guangzhou 510630,China)

机构地区：[1]南方医科大学珠江医院肝胆外科,广州510260 [2]南方医科大学第三附属医院肝胆外科,广州510630

出　　处：《中华肝脏外科手术学电子杂志》2024年第6期894-897,共4页Chinese Journal of Hepatic Surgery(Electronic Edition)

基　　金：广东省自然科学基金面上项目(2023A1515012906,2024A1515011531);广州市科技计划项目(202206010093)

摘　　要：肝脏具有特殊的再生能力,部分切除术后,剩余肝脏可通过再生机制实现肝脏总体积的部分或完全恢复,以维持机体生理需求。因此,肝切除术前对剩余肝再生能力的评估和预测是保证患者围手术期安全的关键。目前肝再生的研究多集中于活体肝移植供/受体的剩余肝再生能力评估,对肝再生机制的研究仍然停留在动物实验水平。精准肝切除术虽然要求术前对剩余肝体积进行评估以确认最大肝切除范围,但未指出如何进行剩余肝功能的术前预测。随着影像组学及人工智能的发展,有望探索出更加精准的肝切除中剩余肝再生能力的评估与预测体系。The liver has a specific ability to regenerate.After partial resection,the total volume of residual liver can be partially or completely restored through the regenerative mechanism to maintain the physiological requirements of the body.Therefore,evaluation and prediction of residual liver regeneration ability before hepatectomy is the key to ensure perioperative safety of patients.At present,researches on liver regeneration primarily focus upon the evaluation of residual liver regeneration ability of donors/recipients in living donor liver transplantation,and researches of liver regeneration mechanism still stuck in the stage of animal experiments.Although precise hepatectomy requires preoperative assessment of the residual liver volume to confirm the maximal range of liver resection,how to predict preoperative function of the residual liver remains poorly understood.With the advancement of radiomics and artificial intelligence,it is expected to explore a more precise evaluation and prediction system of residual liver regeneration ability for hepatectomy.

关 键 词：肝切除术 剩余肝 肝再生 肝肿瘤 

分 类 号：R657.3[医药卫生—外科学]