甲型流感病毒跨宿主传播影响因素研究进展  

Progress on Factors Affecting Cross-host Transmission of Influenza A Viruses

作　　者：孟博 马巍威 MENG Bo;MA Weiwei(School of Chemistry and Life Science,Anshan Normal University,Anshan 114007,China;Graduate School of Anshan Normal University,Anshan 114007,China)

机构地区：[1]鞍山师范学院化学与生命科学学院,辽宁鞍山114007 [2]鞍山师范学院研究生学院,辽宁鞍山114007

出　　处：《西北民族大学学报(自然科学版)》2025年第1期61-69,共9页Journal of Northwest Minzu University(Natural Science)

基　　金：鞍山师范学院校级科学研究项目(24rczx02)。

摘　　要：甲型流感病毒(Influenza A viruses,IAVs)是危害人类和动物健康的主要病原之一,可通过基因重组和基因突变两种方式在自然界中不断进化,进而突破宿主屏障,扩大宿主范围,感染各种家禽、哺乳动物甚至人类,造成跨宿主传播.文章就影响IAVs跨宿主传播因素的相关研究进行了综述,为IAVs的防控提供理论基础.Influenza A viruses(IAVs)are one of the main pathogens that pose a threat to human and animal health.Gene recombination and gene mutation are two ways by which IAVs evolve in nature.IAVs continuously break through the host barrier via the genetic recombination and mutation.This expands the host range and infects various poultry,mammals,and even humans,causing cross-host transmission.This article reviews the relevant research on factors affecting host adaptation and cross-host transmission of IAVs,which provides a theoretical basis for the prevention and control of IAVs.

关 键 词：甲型流感病毒 宿主适应性 跨宿主传播 分子机制 防控 

分 类 号：S855.3[农业科学—临床兽医学]