归芎活血行气汤联合甲钴胺治疗神经根型颈椎病临床研究  

Clinical Study on Guixiong Huoxue Xingqi Decoction Combined with Methylcobalamin for Cervical Spondylotic Radiculopathy

作　　者：刘伟杰 菅炎鹏 王一公 李根锋 姬康祁 连笑宇 樊骏 王令飞 LIU Weijie;JIAN Yanpeng;WANG Yigong;LI Genfeng;JI Kangqi;LIAN Xiaoyu;FAN Jun;WANG Lingfei(Xuchang Central Hospital,Xuchang Henan 461000,China)

机构地区：[1]许昌市中心医院,河南许昌461000

出　　处：《新中医》2025年第6期46-50,共5页New Chinese Medicine

基　　金：河南省科技公关计划项目(LHGJ20191400)。

摘　　要：目的:观察归芎活血行气汤联合甲钴胺治疗神经根型颈椎病(CSR)的临床疗效。方法:将2022年3月—2024年2月许昌市中心医院收治的94例CSR患者按随机数字表法分为甲钴胺组47例,联合组47例。甲钴胺组单纯使用甲钴胺治疗;联合组采用甲钴胺联合归芎活血行气汤治疗。比较2组颈椎功能、椎-基底动脉血流、颈部肌肉张力和临床疗效。结果:治疗后,2组左、右侧椎动脉,基底动脉的平均血流速(VM)、收缩期峰值流速(PSV)均高于治疗前,搏动指数(PI)均低于治疗前,且联合组左、右侧椎动脉,基底动脉的VM、PSV均高于甲钴胺组,PI低于甲钴胺组,差异均有统计学意义(P<0.05);治疗后,2组颈部肌肉张力均高于治疗前,且联合组颈部肌肉张力高于甲钴胺组,差异均有统计学意义(P<0.05);治疗后,2组日本骨科协会(JOA)评分均高于治疗前,且联合组评分高于甲钴胺组,差异均有统计学意义(P<0.05);临床疗效总有效率联合组95.74%(45/47),甲钴胺组70.21%(33/47),2组比较,差异有统计学意义(P<0.05)。结论:归芎活血行气汤联合甲钴胺能够有效改善CSR患者的椎-基底动脉血流,增强颈部肌肉张力,改善颈椎功能,提高临床疗效。Objective:To observe the clinical effect of Guixiong Huoxue Xingqi Decoction combined with Methylcobalamin in the treatment of cervical spondylotic radiculopathy(CSR).Methods:A total of 94 CSR patients admitted to Xuchang Central Hospital from March 2022 to February 2024 were divided into a Methylcobalamin group and a combination group using the random number table method,with 47 cases in each group.The Methylcobalamin group was treated with Methylcobalamin alone,and the combination group was treated with Methylcobalamin combined with Guixiong Huoxue Xingqi Decoction.Cervical spine function,vertebrobasilar artery blood flow,cervical muscle tension,and clinical effects were compared between the two groups.Results:After treatment,the average blood flow velocity(VM)and peak systolic velocity(PSV)of the left and right vertebral arteries and basilar artery in both groups were higher than those before treatment,and the pulsatility index(PI)was lower than that before treatment;the VM and PSV of the left and right vertebral arteries and basilar artery in the combination group were higher than those in the Methylcobalamin group,and the PI was lower than that in the Methylcobalamin group,with differences being significant(P<0.05).After treatment,the neck muscle tension in the two groups was higher than that before treatment,and the neck muscle tension in the combination group was higher than that in the Methylcobalamin group,with differences being significant(P<0.05).After treatment,the Japanese Orthopedic Association(JOA)scores in the two groups were higher than those before treatment,and the combination group had higher scores than the Methylcobalamin group,with differences being significant(P<0.05).The total clinical effective rate was 95.74%(45/47)in the combination group and 70.21%(33/47)in the Methylcobalamin group,with the difference being significant(P<0.05).Conclusion:The combination of Guixiong Huoxue Xingqi Decoction and Methylcobalamin can effectively improve the blood flow of the vertebrobasilar arteries in CS

关 键 词：神经根型颈椎病 归芎活血行气汤 甲钴胺 椎-基底动脉血流 肌肉张力 颈椎功能 

分 类 号：R681.53[医药卫生—骨科学]