THRIVE技术用于单人无面罩全麻诱导对患者脑氧变化及术后认知功能的影响  

Effect of THRIVE Technique on Cerebral Oxygen Change and Postoperative Cognitive Function in Patients with General Anesthesia Without Mask Induction by Single Person

作　　者：蔡俊 闵昱源 CAI Jun;MIN Yuyuan(The Second Department of Anesthesiology and Surgery,Baoji Central Hospital,Baoji 721000,Shaanxi,China;Anesthesia and Perioperative Medical Center of Xi′an People′s Hospital/Xi′an Fourth Hospital,Xi′an 710000,Shaanxi,China)

机构地区：[1]宝鸡市中心医院麻醉手术科二科,陕西宝鸡721000 [2]西安市人民医院/西安市第四医院麻醉与围手术期医学中心,陕西西安710000

出　　处：《医学信息》2025年第5期132-135,共4页Journal of Medical Information

基　　金：陕西省自然科学基础研究计划项目(编号:2023-JC-YB-652)。

摘　　要：目的探究THRIVE技术用于单人无面罩全麻诱导对患者脑氧变化及术后认知功能的影响。方法选取2021年10月-2022年10月于宝鸡市中心医院全身麻醉下实施手术的患者90例,采用随机数字表法分为HFNO组、NOT组、THRIVE组,每组30例。HFNO组使用加压面罩进行预充氧,NOT组使用一次性普通吸氧面罩进行预充氧,THRIVE组使用OptiFlowTM高流量经鼻导管对患者进行3 min预充氧。INIRS监测局部脑氧饱和度(rScO_(2)),应用MMSE、连线测试及凹槽拼板测试评估患者术前及术后24 h的认知功能变化。结果三组经预充氧后rScO_(2)均较入室后提升,全麻诱导后rScO_(2)均较预充氧后下降,差异有统计学意义(P<0.05);术中各组患者均未出现rScO_(2)<55%现象。三组术毕及手术苏醒后rScO_(2)比较,差异无统计学意义(P>0.05)。HFNO组与NOT组不同时期rScO_(2)比较,差异无统计学意义(P>0.05)。THRIVE组麻醉诱导后rScO_(2)高于NOT组,差异有统计学意义(P<0.05),术毕及苏醒后rScO_(2)比较,差异无统计学意义(P>0.05)。三组手术前及术后各时段MMSE评分及认知障碍发生率比较,差异均无统计学意义(P>0.05)。三组术前及术后24 h连线测试和凹槽拼版测试时间比较,差异均无统计学意义(P>0.05)。结论THRIVE技术用于单人无面罩全麻诱导,能降低麻醉诱导对脑氧的影响,且未见明显术后认知障碍。Objective To explore the effect of THRIVE technique on cerebral oxygen changes and postoperative cognitive function in patients with general anesthesia without mask induction by single person.Methods A total of 90 patients who underwent surgery under general anesthesia in Baoji Central Hospital from October 2021 to October 2022 were selected and divided into HFNO group,NOT group and THRIVE group by random number table method,with 30 patients in each group.The HFNO group was pre-oxygenated using a pressurized mask,the NOT group was pre-oxygenated using a disposable ordinary oxygen mask,and the THRIVE group was pre-oxygenated for 3 minutes using an OptiFlowTM high-flow nasal catheter.Regional cerebral oxygen saturation(rScO_(2))was monitored by INIRS.The changes of cognitive function before and 24 hours after operation were evaluated by MMSE,connection test and groove plate test.Results The rScO_(2) of the three groups after pre-oxygenation was higher than that after entering the room,and the rScO_(2) after induction of general anesthesia was lower than that after pre-oxygenation,the difference was statistically significant(P<0.05);there was no phenomenon of rScO_(2)<55% in each group during the operation,and there was no significant difference in rScO_(2) between the three groups after operation and after recovery(P>0.05).There was no significant difference in rScO_(2) between HFNO group and NOT group in different periods(P>0.05).The rScO_(2) after anesthesia induction in the THRIVE group was higher than that in the NOT group,and the difference was statistically significant(P<0.05),but there was no significant difference in rScO_(2) between the two groups after operation and after recovery(P>0.05).There was no significant difference in MMSE score and incidence of cognitive impairment among the three groups before and after operation(P>0.05).There was no significant difference in the time of connection test and groove puzzle test among the three groups before and 24 h after operation(P>0.05).Conclusion THRIVE techn

关 键 词：单人无面罩全麻诱导 脑氧变化 认知功能 THRIVE技术 

分 类 号：R614.2[医药卫生—麻醉学]