基于“阳化气-肺-脾-肾”理论研究黄芪促椎间盘重吸收作用机制  

Mechanism of Astragali Radix in Promoting the Resorption of Intervertebral Discs Herniation Based on“Yang Transforming Qi-lung-spleen-kidney”

作　　者：吴曾涵 邝涛[2] 邝高艳[2] WU Zenghan;KUANG Tao;KUANG Gaoyan(First Clinical College of Traditional Chinese Medicine,Hunan University of Chinese Medicine,Changsha 410007,China;The First Hospital of Hunan University of Chinese Medicine,Changsha 410007,China)

机构地区：[1]湖南中医药大学第一中医临床学院,长沙410007 [2]湖南中医药大学第一附属医院,长沙410007

出　　处：《世界中医药》2025年第1期99-104,共6页World Chinese Medicine

基　　金：国家自然科学基金面上项目(82274543);湖南省教育厅重点项目(23A0285);湖南省中医药管理局重点项目(C2022022)。

摘　　要：黄芪具有补气升阳的功效,是目前非手术治疗腰椎间盘突出症中促椎间盘重吸收的重要药物。通过结合“阳化气,阴成形”“肺-脾-肾”轴和“营卫之气”等中医理论及经络学说,初步构建了“阳化气-肺-脾-肾”免疫调节体系,该体系中包括黄芪归经靶向作用于肺、脾、肾三脏和对营卫物质转化、免疫系统的影响,并以此为基础阐释黄芪促椎间盘重吸收的作用机制,进一步丰富了黄芪临床应用的中医理论基础。Astragali Radix is known for its ability to tonify qi and raise yang,making it an important medicine in the non-surgical treatment of lumbar disc herniation by promoting intervertebral disc resorption.By integrating traditional Chinese medicine(TCM)theories such as“yang transforming qi while yin constituting form”,the“lung-spleen-kidney”axis,and the“nutritive and defensive qi”concept,a preliminary“yng transforming qi-lung-spleen-kidney”immune regulation system is constructed.This system encompasses the targeting effect of Astragali Radix on the lung,spleen,and kidney meridians,as well as its influence on the transformation of nutritive and defensive substances and the immune system.Based on this framework,the mechanism by which Astragali Radix promotes intervertebral disc resorption is further elaborated,enriching the TCM theoretical foundation for its clinical application.

关 键 词：黄芪 “阳化气-肺-脾-肾”免疫调节体系 椎间盘重吸收 腰椎间盘突出症 扶阳抑阴法 “肺-脾-肾”轴 经络学说 中医 作用机制 

分 类 号：R681.53[医药卫生—骨科学]