基于光学相干断层技术的妊娠期高血压疾病对胎盘绒毛的影响研究  

Study on the impact of pregnancy-induced hypertension on placental villi based on optical co-herence tomography technology

作　　者：叶莉丽 梅劼 YE Li-li;MEI Jie(Department of Obstetrics and Gynecology,Affiliated Hospital of Southwest Medical University,Luzhou 646000,China;Department of Obstetrics and Gynecology,Sichuan Academy of Medical Sciences&Sichuan Provincial People's Hospital(Affiliated Hospital of University of Electronic Science and Technology of China),Chengdu 610072,China)

机构地区：[1]西南医科大学附属医院妇产科,四川泸州646000 [2]四川省医学科学院·四川省人民医院(电子科技大学附属医院)妇产科,四川成都610072

出　　处：《实用医院临床杂志》2025年第2期66-70,共5页Practical Journal of Clinical Medicine

基　　金：四川省科技厅重点研发项目(编号:2023YFS0039,2023MS610)。

摘　　要：目的探讨利用光学相干断层三维成像技术研究妊娠期高血压疾病对胎盘绒毛形态的影响。方法选取自2021年8月至2024年2月于四川省人民医院住院分娩的患者,根据纳排标准分别纳入妊娠期高血压组、子痫前期组、妊娠合并慢性高血压组、慢性高血压合并子痫前期组和正常妊娠组各4例。使用光学相干断层三维成像技术测量胎盘绒毛的数据;使用SPSS分析胎盘绒毛数据的差异。结果通过光学相干断层成像技术展示了胎盘绒毛的三维形态学结构,妊娠合并慢性高血压组及慢性高血压合并子痫前期组中间绒毛直径较正常妊娠组粗大(P<0.05),妊娠期高血压组及子痫前期组的中间绒毛直径、终末绒毛直径及终末绒毛长度较正常妊娠组细小(P<0.05),四组高血压疾病的胎盘绒毛分支数量均少于正常妊娠组(P<0.05)。结论光学相干断层成像技术在观察不同妊娠期高血压疾病对胎盘绒毛形态的影响方面具有价值意义。Objective To investigate the effect of hypertensive disorder of pregnancy on placental villus morphology by optical coherence tomography(OCT).Methods Patients who were hospitalized and delivered in our hospital from August 2021 to February 2024 were selected.They were divided into a gestational hypertension group,a preeclampsia group,a chronic hypertension group,a chronic hypertension with superimposed preeclampsia group and a non hypertension group according to the admission and exclusion criteria.The data of placental villi were measured by OCT.SPSS was used to analyze the differences of placental villi data.Results The three-dimensional morphological structure of placental villi was displayed by OCT technology.The diameter of intermediate villi in the pregnancy complicated with chronic hypertension and the chronic hypertension with superimposed preeclampsia group was larger than that in the non hypertension group(P<0.05).The diameter of intermediate villi,the diameter of terminal villi and the length of terminal villi in the gestational hypertension and preeclampsia groups were smaller than that in the non hypertension group(P<0.05).The number of branches of placental villi in the four groups of hypertensive disorder of pregnancy were less than that in the non hypertension group(P<0.05).Conclusion OCT is of great value in observing the effect of different hypertensive disorders of pregnancy on the morphology of placental villi.

关 键 词：妊娠期高血压疾病 光学相干断层扫描 胎盘绒毛 

分 类 号：R71[医药卫生—妇产科学]