缩宫素联合卡前列素氨丁三醇注射液治疗宫缩乏力性产后出血的临床疗效  

Clinical efficacy of oxytocin combined with carboprost tromethamine injection in the treatment of postpartum hemorrhage caused by uterine atony

作　　者：姜海雁 Jiang Haiyan(Department of Obstetrics,Gangbei District People's Hospital,Guigang 537100,China)

机构地区：[1]贵港市港北区人民医院产科,广西贵港537100

出　　处：《实用妇科内分泌电子杂志》2024年第22期43-46,共4页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探究缩宫素联合卡前列素氨丁三醇注射液在宫缩乏力性产后出血产妇中的应用成效。方法将40例宫缩乏力性产后出血产妇,随机分为参照组(20例,缩宫素)及干预组(20例,缩宫素联合卡前列素氨丁三醇注射液),比较两组临床疗效、临床指标、血细胞指标及不良反应发生情况。结果干预组总有效率(100%)比参照组高(80.00%)(P<0.05)。干预组第三产程时间(6.23±1.18)h比参照组(11.46±1.25)h短,产后30 min、2 h及24 h出血量(266.62±30.47)ml、(316.48±30.31)ml、(364.14±40.03)ml均比参照组(325.44±30.67)ml、(385.13±30.30)ml、(467.60±40.22)ml少(P<0.05)。分娩后,干预组血红蛋白(Hb)、红细胞比容(HCT)水平均比参照组更佳(P<0.05)。两组不良反应发生率对比,差异无统计学意义(P>0.05)。结论缩宫素与卡前列素氨丁三醇注射液在宫缩乏力性产后出血产妇中联合使用,可以有效减少产后出血量并缩短分娩时间,提升疗效,恢复血细胞指标,同时具有安全性,值得临床应用。Objective To exploring the efficacy of oxytocin combined with carboprost tromethamine injection in women experiencing uterine atony-related postpartum hemorrhage.Methods 40 postpartum hemorrhage women with uterine atony were selected and randomly divided into the reference group(20 cases,oxytocin)and the intervention group(20 cases,oxytocin combined with carboprost tromethamine injection)using a random number table method.The clinical efficacy,clinical indicators,blood cells,and incidence of adverse reactions were compared between the two groups.Results The overall effective rate in the intervention group(100%)was higher than that in the control group(80.00%)(P<0.05).The duration of the third stage of labor in the intervention group(6.23±1.18)h was shorter than that in the control group(11.46±1.25)h.The blood loss at 30 minutes,2 hours,and 24 hours postpartum in the intervention group(266.62±30.47)ml,(316.48±30.31)ml,(364.14±40.03)ml was less than that in the control group(325.44±30.67)ml,(385.13±30.30)ml,(467.60±40.22)ml(P<0.05).Postpartum,the levels of hemoglobin(Hb)and hematocrit(HCT)in the intervention group were better than those in the control group(P<0.05).The comparison of adverse reaction rates between the two groups showed no statistically significant difference(P>0.05).Conclusion The combined use of oxytocin and carboprost tromethamine injection in women experiencing uterine atony-related postpartum hemorrhage can effectively reduce postpartum bleeding,shorten delivery time,enhance therapeutic efficacy,restore blood cell parameters,and maintain safety,making it worthy of clinical application.

关 键 词：缩宫素 卡前列素氨丁三醇 宫缩乏力 产后出血 

分 类 号：R47[医药卫生—护理学]