基于生物-心理-社会功能的路径化护理在经肝动脉化疗栓塞治疗原发性肝癌患者中的应用效果  

Application Effect of Pathway Nursing Based on Bio-psycho-social Function in Primary Liver Cancer Patients Undergoing Transcatheter Arterial Chemoembolization

作　　者：孙佳欢 谢明晖 SUN Jiahuan;XIE Minghui(Department of Interventional Therapy,the First Affiliated Hospital of Naval Medical University,Shanghai 200433,China;不详)

机构地区：[1]海军军医大学第一附属医院介入治疗科,上海200433

出　　处：《中国医学创新》2025年第8期67-71,共5页Medical Innovation of China

摘　　要：目的:探究基于生物-心理-社会功能的路径化护理在经肝动脉化疗栓塞治疗原发性肝癌患者中的应用效果。方法:选择2021年1月—2023年1月在海军军医大学第一附属医院接受经肝动脉化疗栓塞治疗的原发性肝癌患者62例,应用随机数字表法将其分为对照组(接受常规护理)及观察组(接受基于生物-心理-社会功能的路径化护理),各31例。对比两组恢复指标、心理状态[疾病不确定感量表(MUIS)、状态焦虑量表(SAI)]、生活质量[癌症患者生命质量测定量表之肝癌量表(QLICP-LI)]、免疫功能(CD3^(+)、CD4^(+)、CD8^(+))、应激反应[C 反应蛋白(CRP)、皮质醇(Cor)]。结果:观察组首次离床活动时间早于对照组,首次离床活动持续时间长于对照组,差异均有统计学意义(P<0.05)。护理后,两组MUIS、SAI评分均降低,QLICP-LI评分均升高,观察组MUIS、SAI评分均低于对照组,QLICP-LI评分高于对照组,差异均有统计学意义(P<0.05)。护理后,两组CD3^(+)、CD4^(+)均升高,CD8^(+)均降低,观察组CD3^(+)、CD4^(+)均高于对照组,CD8^(+)低于对照组,差异均有统计学意义(P<0.05)。术后1、3 d,两组CRP、Cor均升高,但观察组均低于对照组,差异均有统计学意义(P<0.05)。结论:经肝动脉化疗栓塞治疗原发性肝癌患者接受基于生物-心理-社会功能的路径化护理,可减轻应激反应,改善免疫功能、心理状态,促进术后恢复。Objective:To explore the application effect of pathway nursing based on bio-psycho-social function in primary liver cancer patients undergoing transcatheter arterial chemoembolization.Method:A total of 62 patients with primary liver cancer who underwent transcatheter arterial chemoembolization in the First Affiliated Hospital of Naval Medical University from January 2021 to January 2023 were selected and divided into control group(received conventional nursing)and observation group(received pathway nursing based on bio-psycho-social function)by random number table method,with 31 cases in each group.Recovery indexes,psychological status[Mishel uncertainty in illness scale(MUIS),state anxiety inventory(SAI)],quality of life[quality of life instrument for cancer patients-liver cancer(QLICP-LI)],immune function(CD3^(+),CD4^(+),CD8^(+)),stress response[C reactive protein(CRP),cortisol(Cor)]were compared between the two groups.Result:The first time of getting out of bed in the observation group was earlier than that in the control group,and the duration of the first time of getting out of bed was longer than that in the control group,the differences were statistically significant(P<0.05).After nursing,MUIS and SAI scores were decreased in both groups,QLICP-LI scores were increased,and MUIS and SAI scores in observation group were lower than those in control group,QLICP-LI score was higher than that in control group,the differences were statistically significant(P<0.05).++After nursing,CD3 and CD4 were increased in both+++groups,CD8 were decreased,and CD3 and CD4 in the observation group were higher than those in the control+group,CD8 was lower than that in the control group,the differences were statistically significant(P<0.05).1 and 3 d after surgery,CRP and Cor were increased in both groups,and those in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).Conclusion:Primary liver cancer patients undergoing transcatheter arterial chemoembolization rece

关 键 词：生物-心理-社会功能 路径化护理 经肝动脉化疗栓塞 原发性肝癌 并发症 

分 类 号：R47[医药卫生—护理学]