降钙素原、乳酸清除率及红细胞分布宽度在老年重症肺炎患者预后评估中的应用价值研究  

Application Value of Procalcitonin,Lactate Clearance and Red Blood Cell Distribution Width in Prognosis Assessment of Elderly Patients with Severe Pneumonia

作　　者：刘滨[1] 黄彩英 曾唯波 钟穗斌 LIU Bin;HUANG Caiying;ZENG Weibo;ZHONG Suibin(Department of Intensive Care Medicine,Guangdong Central Hospital of Reclamation,Zhanjiang,Guangdong 524000,China)

机构地区：[1]广东省农垦中心医院重症医学科,广东湛江524000

出　　处：《中国医药指南》2025年第9期11-13,共3页Guide of China Medicine

基　　金：2023年度第二批湛江市非资助科技攻关计划项目(2023B01121)。

摘　　要：目的研究降钙素原、乳酸清除率及红细胞分布宽度在老年重症肺炎患者预后评估中的应用价值。方法选取2023年7月至2024年8月广东省农垦中心医院收治的100例老年重症肺炎患者,在所有患者入院后对其进行降钙素原、乳酸清除率及红细胞分布宽度检测,并形成规范记录,对所有重症肺炎患者进行随访,根据随访后观察患者最后的预后结果,将其分为存活组(80例)和死亡组(20例),统计汇总相关指标数据,利用专业医学统计软件处理分析,观察对比不同组别患者上述降钙素原、乳酸清除率及红细胞分布宽度指标水平差异。结果入院第1天、第3天,两组比较降钙素原水平无统计学意义(P>0.05);入院第5天、第7天,存活组的降钙素原水平低于死亡组(P<0.05);入院第1天,两组比较乳酸清除率水平无统计学意义(P>0.05);入院第3天、第5天、第7天,存活组的乳酸清除率高于死亡组(P<0.05);入院第1天、第3天,两组比较红细胞分布水平无统计学意义(P>0.05);入院第5天、第7天,存活组的红细胞分布宽度水平低于死亡组(P<0.05)。结论对于老年重症肺炎患者来说,动态监测降钙素原、乳酸清除率及红细胞分布宽度水平,对患者病情严重程度可综合判定,对评估患者预后有重要意义。Objective To study the clearance rate of procalcitonin and lactic acid and the application value of red blood cell distribution width in the prognosis evaluation of elderly patients with severe pneumonia.Methods Data were collected from 100 elderly patients with severe pneumonia admitted to our hospital from July 2023 to August 2024.After all patients were admitted to the hospital,procalcitonin,lactate clearance rate and red blood cell distribution width were detected,and standardized records were formed.All patients with severe pneumonia were followed up.According to the final prognosis of patients observed after follow-up,they were divided into survival group(80 cases)and death group(20 cases),and relevant index data were statistically summarized.Using professional medical statistical software to analyze,observe and compare the differences of procalcitonin,lactic acid clearance rate and red blood cell distribution width index level in different groups of patients.Results There was no statistical significance in procalcitonin level between the two groups on day 1 and day 3 of admission(P>0.05).On day 5 and day 7,the level of procalcitonin in survival group was lower than that in death group(P<0.05).On the first day of admission,there was no statistical significance in lactic acid clearance between the two groups(P>0.05).On day 3,day 5 and day 7,the lactic acid clearance rate of survival group was higher than that of death group(P<0.05).On day 1 and day 3,there was no statistical significance in erythrocyte distribution between the two groups(P>0.05).On the 5th and 7th day of admission,the erythrocyte distribution width in the survival group was lower than that in the death group(P<0.05).Conclusions For the elderly patients with severe pneumonia,dynamic monitoring of procalcitonin,lactate clearance rate and red blood cell distribution width level can comprehensively judge the severity of the patient’s illness and is of great significance for evaluating the prognosis of the patient.

关 键 词：降钙素原 乳酸清除率 红细胞分布宽度 重症肺炎 预后评估 

分 类 号：R563.1[医药卫生—呼吸系统]