门冬氨酸钾镁与胺碘酮联合治疗急性心肌梗死室性心律失常的疗效  

The Efficacy of Potassium Magnesium Aspartate Combined with Amiodarone in the Treatment of Ventricular Arrhythmias in Acute Myocardial Infarction

作　　者：孙苓玉 SUN Lingyu(Department of Cardiology,Liaoning Liaoyang Central Hospital,Liaoyang,Liaoning 111000,China)

机构地区：[1]辽宁省辽阳市中心医院心内科,辽宁辽阳111000

出　　处：《中国医药指南》2025年第9期97-99,共3页Guide of China Medicine

摘　　要：目的讨论针对急性心肌梗死室性心律失常患者开展门冬氨酸钾镁与胺碘酮联合治疗的效果。方法急性心肌梗死室性心律失常患者临床资料取自辽宁省辽阳市中心医院心内科特定时段(2023年5月至2024年5月),共计80例,随机数字表法分组,每组40例;对照组予以胺碘酮治疗,观察组采取门冬氨酸钾镁与胺碘酮联合治疗。统计纳入不同组别患者的临床疗效、血液流变学指标、心功能和不良事件发生情况。结果针对不同组别患者的临床疗效,观察组明显较高(P<0.05);治疗后观察组患者血液流变学指标水平明显比对照组低(P<0.05);治疗后观察组患者LVEF水平较高,LVESD水平较对照组低(P<0.05);对比各组患者的不良事件发生率,观察组更低(P<0.05)。结论开展门冬氨酸钾镁与胺碘酮联合治疗方案,可以进一步提高患者临床疗效,改善患者血流动力学状况及心功能,同时可有效减少患者不良事件发生率。Objective To discuss the effect of combined treatment with potassium magnesium aspartate and amiodarone in patients with ventricular arrhythmias following acute myocardial infarction.Methods Clinical data of patients with acute myocardial infarction and ventricular arrhythmias were collected from the Department of Cardiology of Liaoyang Central Hospital in Liaoning Province during a specific period(from May 2023 to May 2024).A total of 80 patients were randomly divided into two groups using a random number table method,with 40 patients in each group.The control group received amiodarone treatment,while the observation group received a combination of potassium magnesium aspartate and amiodarone.The clinical efficacy,blood rheology indicators,cardiac function,and the occurrence of adverse events were statistically analyzed.Results The clinical efficacy in the observation group was significantly higher than in the control group(P<0.05).After treatment,the blood rheology indicators in the observation group were significantly lower than those in the control group(P<0.05).The left ventricular ejection fraction(LVEF)in the observation group was higher,and the left ventricular endsystolic diameter(LVESD)was lower than that of the control group(P<0.05).The incidence of adverse events was lower in the observation group compared to the control group(P<0.05).Conclusions The combined treatment of potassium magnesium aspartate and amiodarone can significantly improve clinical efficacy,enhance blood hemodynamics and cardiac function,and effectively reduce the incidence of adverse events in patients.

关 键 词：急性心肌梗死室性心律失常 门冬氨酸钾镁 胺碘酮 心功能 血液流变学指标 不良事件发生情况 

分 类 号：R542.22[医药卫生—心血管疾病] R541.7[医药卫生—内科学]