肾移植受者妊娠管理的最佳证据总结  

Best evidence summary for pregnancy management in renal transplant recipients

作　　者：赵雯静 管晓红 张海玲 余娟 储爱琴 葛文静 石珂 ZHAO Wenjing;GUAN Xiaohong;ZHANG Hailing;YU Juan;CHU Aiqin;GE Wenjing;SHI Ke(Dept.of Renal Transplantation,the First Affiliated Hospital of University of Science and Technology of China,Anhui Provincial Hospital,Hefei 230001,China;Dept.of Nursing Administration,the First Affiliated Hospital of University of Science and Technology of China,Anhui Provincial Hospital,Hefei 230001,China)

机构地区：[1]中国科学技术大学附属第一医院(安徽省立医院)肾移植科,安徽合肥230001 [2]中国科学技术大学附属第一医院(安徽省立医院)护理部,安徽合肥230001

出　　处：《护理学报》2025年第6期32-37,共6页Journal of Nursing(China)

基　　金：安徽省护理学会重点基金项目(AHHL a202101);蚌埠医科大学研究生科研创新计划项目(Byycx 22080)。

摘　　要：目的总结肾移植受者妊娠管理的相关证据。方法根据PIPOST模式构建肾移植受者妊娠管理循证问题。按照“6S”证据金字塔自上而下系统地检索国内外指南网、协会网站及数据库中关于肾移植受者妊娠管理的相关证据。检索时限为建库至2024年1月30日。由2名研究者进行文献质量评价和汇总证据。结果共纳入15篇文献,包括临床决策1篇、实践指南5篇、专家共识5篇及系统评价4篇。最终从团队组建、避孕管理、妊娠时机、妊娠期用药管理、哺乳期用药管理、妊娠期随访管理及分娩时机7个方面汇总31条证据。结论本研究基于循证方法学系统汇总了肾移植受者妊娠管理的相关证据,以期有效指导肾移植受者,规避妊娠相关风险,改善母婴结局,保障母儿安全。Objective To summarize the evidence related to pregnancy management in renal transplant recipients.Methods Evidence-based questions on pregnancy management in renal transplant recipients were constructed according to the PIPOST model.The evidence on pregnancy management in renal transplant recipients was systematically searched in accordance with the"6S"pyramid in guideline networks,association websites,and databases at home and abroad.The retrieval period spanned from the inception to January 30,2024.Literature quality assessment and summarization of the evidence were performed by two researchers.Results A total of 15 papers were included,including 1 clinical decision,5 guidelines,5 expert consensus and 4 systematic evaluations,and 31 pieces of evidence were summarized into 7 areas:team formation,contraceptive management,timing of pregnancy,medication management during pregnancy,medication management during lactation,follow-up management during pregnancy,and timing of delivery.Conclusion This study systematically summarizes the evidence related to pregnancy management in renal transplant recipients based on evidence-based method,with the aim of effectively guiding renal transplant recipients to avoid pregnancy-related risks,improve maternal and infant outcomes,and safeguard maternal and child safety.

关 键 词：肾移植 妊娠 管理 循证护理 证据总结 

分 类 号：R473.6[医药卫生—护理学]