内镜下圈套器冷切除术治疗胃息肉患者的效果  

Effects of endoscopic cold snare polypectomy in treatment of patients with gastric polyps

作　　者：高瑞华 GAO Ruihua(Department of Gastroenterology of Jinshui District General Hospital,Zhengzhou 450000 Henan,China)

机构地区：[1]郑州市金水区总医院消化科,河南郑州450000

出　　处：《中国民康医学》2025年第6期36-38,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:观察内镜下圈套器冷切除术(CSP)治疗胃息肉患者的效果。方法:回顾性分析2021年5月至2024年1月该院收治的92例胃息肉患者的临床资料,根据手术方法不同将其分为对照组和观察组各46例。对照组给予内镜下高频电切术(HFE)治疗,观察组给予内镜下CSP治疗。比较两组围手术期指标(手术时间、住院时间)水平,术前、术后14 d胃功能指标[胃蛋白酶原Ⅰ(PGⅠ)、胃蛋白酶原Ⅱ(Ⅱ)、胃泌素-17(G-17)]水平,术前、术后1 d炎性因子[白细胞介素-6(IL-6)、白细胞介素-9(IL-9)、白细胞介素-17(IL-17)]水平,以及并发症发生率。结果:观察组手术时间、住院时间均短于对照组,差异有统计学意义(P<0.05);术后14 d,两组PGⅠ、G-17水平均高于术前,且观察组高于对照组,差异有统计学意义(P<0.05);两组PGⅡ水平比较,差异无统计学意义(P>0.05);术后1 d,两组IL-6、IL-9、IL-17水平均高于术前,但观察组低于对照组,差异有统计学意义(P<0.05);观察组并发症发生率为2.17%(1/46),低于对照组的17.39%(8/46),差异有统计学意义(P<0.05)。结论:内镜下CSP治疗胃息肉患者,可缩短手术时间和住院时间,改善胃功能,减轻机体炎症反应,降低并发症发生率,效果优于内镜下HFE治疗。Objective:To observe effects of endoscopic cold snare polypectomy(CSP)in treatment of patients with gastric polyps.Methods:The clinical data of 92 patients with gastric polyps admitted to this hospital from May 2021 to January 2024 were retrospectively analyzed.According to different surgical methods,they were divided into control group and observation group,46 cases in each group.The control group was treated with endoscopic high-frequency electrotomy(HFE),while the observation group was treated with endoscopic CSP.The levels of perioperative indexes(operation time,hospitalization time),gastric function indexes[pepsinogen I(PGI),pepsinogen II(II),gastrin-17(G-17)]before and 14 days after the surgery and inflammatory factors[interleukin-6(IL-6),interleukin-9(IL-9),interleukin-17(IL-17)]levels before and 1 day after the surgery,and the incidence of complications were compared between the two groups.Results:The operation time and the hospitalization time of the observation group were shorter than those of the control group,and the difference was statistically significant(P<0.05).14 days after the surgery,the levels of PGI and G-17 in the two groups were higher than those before the surgery,those in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in the PGII level between the two groups(P>0.05).1 day after the surgery,the levels of IL-6,IL-9 and IL-17 in the two groups were higher than those before the surgery,those in the observation group were lower than those in the control group,but the differences were statistically significant(P<0.05).Further,the incidence of complications in the observation group was 2.17%(1/46),which was lower than 17.39%(8/46)in the control group,and the difference was statistically significant(P<0.05).Conclusions:Endoscopic CSP in the treatment of the patients with gastric polyps can shorten the operation time and the hospitalization time,improve the gastric function,reduce the

关 键 词：内镜下圈套器冷切除术 内镜下高频电切术 胃息肉 胃功能 炎性因子 并发症 

分 类 号：R656.61[医药卫生—外科学]