连花清瘟颗粒联合阿奇霉素治疗肺炎支原体肺炎患儿的效果  

Effects of Lianhua Qingwen granules combined with Azithromycin in treatment of children with mycoplasma pneumoniae pneumonia

作　　者：陈麟 CHEN Lin(Department of Pediatrics of the Affiliated Hospital of Jiaozuo Health and Medicine School,Jiaozuo 454000 Henan,China)

机构地区：[1]焦作卫生医药学校附属医院儿科,河南焦作454000

出　　处：《中国民康医学》2025年第6期96-98,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:观察连花清瘟颗粒联合阿奇霉素治疗肺炎支原体肺炎患儿的效果。方法:选取2019-2023年该院收治的80例肺炎支原体肺炎患儿进行前瞻性研究,按照随机数字表法将其分为对照组和研究组各40例。对照组给予阿奇霉素治疗,研究组在对照组基础上联合连花清瘟颗粒治疗。比较两组临床疗效,临床症状(咳嗽、发热、肺啰音)消失时间,治疗前后肺功能指标[第1秒用力呼气容积(FEV1)、用力肺活量(FVC)]、炎性指标[C反应蛋白(CRP)、白细胞计数(WBC)、中性粒细胞]水平,以及不良反应发生率。结果:研究组治疗总有效率为92.50%(37/40),高于对照组的75.00%(30/40),差异有统计学意义(P<0.05);研究组咳嗽、发热、肺啰音消失时间均短于对照组,差异有统计学意义(P<0.05);治疗后,两组FEV1、FVC水平均高于治疗前,且研究组高于对照组,差异有统计学意义(P<0.05);两组CRP、WBC及中性粒细胞水平均低于治疗前,且研究组低于对照组,差异有统计学意义;两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:连花清瘟颗粒联合阿奇霉素治疗肺炎支原体肺炎患儿可提高临床疗效,促进临床症状消失,改善肺功能,减轻机体炎症反应,效果优于单纯阿奇霉素治疗。Objective:To observe effects of Lianhua Qingwen granules combined with Azithromycin in treatment of children with mycoplasma pneumoniae pneumonia.Methods:A prospective study was conducted on 80 children with mycoplasma pneumoniae pneumonia admitted to the hospital from 2019 to 2023.According to the random number table method,they were divided into control group and study group,40 cases in each group.The control group was treated with Azithromycin,while the study group was treated with Lianhua Qingwen granules on the basis of that of the control group.The clinical efficacy,the disappearance time of clinical symptoms(cough,fever,lung rales),the levels of lung function indexes[forced expiratory volume in one second(FEV1),forced vital capacity(FVC)]and inflammation indexes[C-reactive protein(CRP),white blood cell count(WBC),neutrophils]before and after the treatment,and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of treatment in the study group was 92.50%(37/40),which was higher than 75.00%(30/40)in the control group,and the difference was statistically significant(P<0.05).The disappearance time of cough,fever and pulmonary rales in the study group was shorter than that in the control group,and the difference was statistically significant(P<0.05).After the treatment,the levels of FEV1 and FVC in the two groups were higher than those before the treatment,those in the study group were higher than those in the control group,and the differences were statistically significant(P<0.05).The levels of CRP,WBC and neutrophils in the two groups were lower than those before the treatment,those in the study group were lower than those in the control group,and the differences were statistically significant.However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Lianhua Qingwen granules combined with Azithromycin in the treatment of the children with mycoplasma pneumoniae pneumonia can improve the clinic

关 键 词：连花清瘟颗粒 阿奇霉素 支原体肺炎 炎性指标 肺功能 

分 类 号：R725.6[医药卫生—儿科]