蛇床子素的抗肿瘤作用研究进展  

Progress in Anti-Tumor Effect of Osthole

作　　者：肖春芬[1] Xiao Chunfen(Guangdong Food and Drug Vocational College,Guangzhou 510520,China)

机构地区：[1]广东食品药品职业学院,广东广州510520

出　　处：《广东化工》2025年第4期86-87,83,共3页Guangdong Chemical Industry

基　　金：广东省医学科学技术研究基金项目(A2022545);广东食品药品职业学院自然科学研究项目(2020ZR19)。

摘　　要：蛇床子素是蛇床子中的主要活性成分,具有抗肿瘤、抗炎、抗骨质疏松、神经保护、心血管保护等丰富的药理活性。近年来有较多关于蛇床子素的抗肿瘤作用的报道,其主要研究方向涉及蛇床子素、蛇床子素衍生物、蛇床子素联合放疗、化疗药物抗肿瘤作用及其作用机制。本文对蛇床子素单体抗肿瘤作用、蛇床子素协同抗肿瘤作用及其作用机制的研究进展进行综述,以期为蛇床子素进一步研究提供参考。Osthole is the main active ingredient in cnidium monnieri,which has rich pharmacological activities such as anti-tumor,anti-inflammatory,anti-osteoporosis,neuroprotection and cardiovascular protection,and so on.In recent years,the studies about the anti-tumor effect and mechanism were reported,including osthole,osthole derivatives,osthole combined with radiotherapy and chemotherapy.In this paper,the anti-tumor effect of osthole,the synergistic anti-tumor effect of osthole and its mechanism are summarized,in order to provide a reference for further study on the antitumor effect of osthole.

关 键 词：蛇床子素 抗肿瘤 协同 机制 

分 类 号：R285[医药卫生—中药学]