慢性阻塞性肺疾病病人肠道动力学与生活质量的相关性分析  

Correlation between intestinal dynamics and quality of life in patients with chronic obstructive pulmonary disease

作　　者：曹寅慧 殷稚飞 朱叶 陈子 吴迪 许光旭 CAO Yinhui;YIN Zhifei;ZHU Ye;CHEN Zi;WU Di;XU Guangxu(Department of Rehabilitation Medicine,the First Affiliated Hospital with Nanjing Medical University,Nangjing 210029,China;Department of Respiratory and Critical Care Medicine,the First Affiliated Hospital with Nanjing Medical University,Nangjing 210029,China;School of Rehabilitation Medicine,Nanjing Medical University,Nanjing 211166,China)

机构地区：[1]南京医科大学第一附属医院康复医学中心,江苏省南京市210029 [2]南京医科大学第一附属医院呼吸与危重症医学科,江苏省南京市210029 [3]南京医科大学康复医学院,江苏省南京市211166

出　　处：《实用老年医学》2025年第3期258-262,共5页Practical Geriatrics

摘　　要：目的探讨COPD病人的肠道动力学与生活质量的相关性。方法采用横断面调查的方式,在南京医科大学第一附属医院纳入45例COPD病人,并向社会招募45例健康受试者,使用胃肠动力仪对2组受试者的肠道动力进行检测,采用健康状况调查简表(SF-36)对他们的生理和心理状态进行评估。结果COPD组升结肠、横结肠、降结肠活动的幅值、降结肠蠕动的频率都高于健康组(P<0.05或P<0.01);健康组SF-36中的生理功能(PF)、生理职能(RP)、情感职能(RE)、精力(VT)、社会功能(SF)评分均显著高于COPD组(P<0.01);COPD病人肠道动力与SF-36中的PF、RE、SF、RP、VT等呈负相关(均P<0.05)。结论COPD病人肠道动力学较健康组亢进;肠道动力学的紊乱对COPD病人的生活质量有负面影响。Objective To explore the correlation between intestinal dynamics and quality of life in the patients with chronic obstructive pulmonary disease(COPD).Methods Forty-five patients with COPD at the First Affiliated Hospital with Nanjing Medical University were enrolled by cross-sectional survey,and 45 healthy subjects were recruited from the society.The intestinal motility of the two groups was detected by gastrointestinal motility instrument,and their physiological and psychological status was evaluated by 36-item short form health survey(SF-36)questionnaire.Results The amplitude of ascending colon,transverse colon and the amplitude and frequency of descending colon in COPD group were higher than those in healthy group(P<0.05 or P<0.01).The scores of physical functioning(PF),role physical(RP),role emotional(RE),vitality(VT)and social functioning(SF)in SF-36 of the healthy group were significantly higher than those of COPD group(P<0.01).Intestinal motility was negatively correlated with PF,RE,SF,RP and VT in the patients with COPD(all P<0.05).Conclusions The intestinal motility in the patients with COPD is higher than that in healthy people.The disorder of intestinal dynamics shows a negative impact on the quality of life in the patients with COPD.

关 键 词：慢性阻塞性肺疾病 肠道动力学 生活质量 

分 类 号：R563[医药卫生—呼吸系统]