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作 者:张强 郭柳柳 ZHANG Qiang;GUO Liuliu(Department of Critical Care Medicine,Sanming Hospital of Integrated Chinese and Western Medicine,Sanming 365001,China)
机构地区:[1]三明市中西医结合医院重症医学科,福建三明365001
出 处:《中国医学创新》2025年第7期138-142,共5页Medical Innovation of China
摘 要:目的:探究千金苇茎汤加减治疗痰热型重症肺炎患者的临床效果。方法:选择2022年6月—2024年1月三明市中西医结合医院重症医学科收治的100例痰热型重症肺炎患者,按照随机信封法分两组,各50例。对照组采用标准治疗,研究组在对照组基础上联用千金苇茎汤加减治疗,治疗21 d后,比较两组的临床疗效、肺功能指标及炎症因子水平。结果:研究组治疗总有效率高于对照组,咳嗽、肺啰音和发热消失时间均早于对照组,差异均有统计学意义(P<0.05)。治疗后,研究组第1秒用力呼气容积(FEV1)、用力肺活量(FVC)均高于对照组,且降钙素原(PCT)、C反应蛋白(CRP)、白细胞计数(WBC)水平均低于对照组,差异均有统计学意义(P<0.05)。结论:千金苇茎汤加减辅助治疗痰热型重症肺炎效果较好,能够显著降低患者血清炎症因子水平,减轻肺部炎症反应,提高患者肺功能,改善其预后表现,治疗实用性较高。Objective:To explore the clinical effect of modified Qianjin Weijing Decoction on patients with phlegm-heat severe pneumonia.Method:A total of 100 patients with severe pneumonia of phlegm-heat type admitted to the Critical Care Medicine Department of Sanming Hospital of Integrated Chinese and Western Medicine from June 2022 to January 2024 were selected and divided into two groups according to random envelope method,with 50 cases in each group.The control group was treated with standard treatment,and the study group was treated with modified Qianjin Weijing Decoction.After 21 d of treatment,the clinical efficacy,pulmonary function indexes and levels of inflammatory factors of the two groups were compared.Result:The total effective rate of the study group was higher than that of the control group,and the disappearance time of cough,pulmonary rales and fever were earlier than those of the control group,with statistical significance(P<0.05).After treatment,the forced expiratory volume in 1second(FEV1)and forced vital capacity(FVC)of the study group were higher than those of the control group,and the levels of procalcitonin(PCT),C reactive protein(CRP)and white blood cell count(WBC)of the study group were lower than those of the control group,with statistical significance(P<0.05).Conclusion:Modified Qianjin Weijing Decoction has a good effect in the adjuvant treatment of phlegm-heat severe pneumonia,which can significantly reduce the level of serum inflammatory factors,reduce lung inflammation,improve lung function and improve prognosis of patients,and has high therapeutic practicability.
关 键 词:千金苇茎汤加减 标准治疗 痰热型重症肺炎 炎症刺激
分 类 号:R259[医药卫生—中西医结合]
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