唐山市路北区2020—2024年儿童代谢综合征的分布特征及危险因素分析  

Distribution characteristics and risk factor analysis of metabolic syndrome in children in Lubei district of Tangshan City from 2020 to 2024

作　　者：谷小娜 陈新春[1] 寇永妹[1] 吉国强 GU Xiaona;CHEN Xinchun;KOU Yongmei;JI Guoqiang(Department of Pediatrics,Tangshan People's Hospital,Tangshan 063000,China;Department of Infectious Diseases,Tangshan Seventh Hospital)

机构地区：[1]唐山市人民医院儿科,063000 [2]唐山市第七医院感染科

出　　处：《天津医药》2025年第3期307-311,共5页Tianjin Medical Journal

基　　金：河北省医学科学研究课题计划(20191599)。

摘　　要：目的探讨唐山市路北区2020—2024年儿童代谢综合征(MS)的分布特征及危险因素。方法采用多节段分层整群抽样的方法,确定964名儿童作为研究对象。对所有研究对象进行问卷调查,问卷回收945份,回收率98.0%。比较不同特征人群MS的检出率,通过Logistic回归分析儿童发生MS的危险因素。结果945例儿童中,患MS者49例(5.19%),不同性别检出率比较差异无统计学意义(P>0.05)。7~10岁和11~14岁的不同性别之间收缩压(SBP)、舒张压(DBP)、甘油三酯(TG)及高密度脂蛋白胆固醇(HDL-C)比较差异均无统计学意义(P>0.05),而11~14岁男生的总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)及腰围(WC)高于女生(P<0.05)。MS组患者肥胖、体育活动时间<10 h/周、高血压家族史占比及WC高于非MS组(P<0.05)。多因素Logistic回归模型显示,肥胖、体育活动时间<10 h/周、有高血压家族史及较高的WC是儿童发生MS的独立危险因素(P<0.05)。结论肥胖、有高血压家族史、体育活动时间短及较高的WC与儿童MS的发生关系密切,临床应重点关注。Objective To investigate the clinical distribution and risk factors of metabolic syndrome(MS)in children from Lubei district of Tangshan City from 2020 to 2024.Methods A total of 964 children were identified by multi-segment stratified cluster sampling.A questionnaire survey was conducted on all subjects,and the recovery rate of the questionnaire was 98.0%,with 945 samples recovered.The detection rates of MS in different populations were compared,and risk factors of MS in children were analysed by Logistic regression analysis.Results In 945 children,49(5.19%)had MS,and there was no significant difference in detection rate between different genders of children(P>0.05).There were no significant differences in blood pressure[systolic blood pressure(SBP)and diastolic blood pressure(DBP)],blood lipid[triglycerides(TG)and high density lipoprotein cholesterol(HDL-C)]between children ages 7 to 10 years old and 11 to 14 years old(P>0.05).The values of total cholesterol(TC),low-density lipoprotein cholesterol(LDL-C)and waist circumference(WC)were higher in boys aged 11-14 than those in girls(P<0.05).The proportion of body weight and obesity,the proportion of physical activity time<10 h/week,the proportion of family history of hypertension and WC level were higher in the MS group than those in the non-MS group(P<0.05).Multivariate Logistic regression model showed that weight obesity,physical activity time<10 h/week,family history of hypertension and high WC value were independent risk factors for MS in children(P<0.05).Conclusion Obesity,family history of hypertension,time spent in physical activity and higher WC are strongly associated with the development of MS in children,and clinical attention should be paid to them.

关 键 词：代谢综合征 儿童 危险因素 LOGISTIC模型 

分 类 号：R174.6[医药卫生—妇幼卫生保健]