皮下填充微交联透明质酸改善眶下区衰老的疗效观察  

Observation of the efficacy of subcutaneous filling with micro-cross-linked hyaluronic acid for infraorbital rejuvenation

作　　者：谢恒 黄莉宁 XIE Heng;HUANG Lining(Dermatology Hospital,Southern Medical University,Guangzhou 510091,China)

机构地区：[1]南方医科大学皮肤病医院,广东广州510091

出　　处：《皮肤性病诊疗学杂志》2025年第2期102-107,共6页Journal of Diagnosis and Therapy on Dermato-venereology

基　　金：广东省医学科学技术研究基金(A2021059)。

摘　　要：目的评估皮下填充微交联透明质酸(MCLHA)改善眶下区衰老的疗效与安全性。方法2022年3月至2023年6月在南方医科大学皮肤病医院纳入37例泪槽沟合并下睑袋的患者,根据分型确定MCLHA在眶下区的填充治疗方案。治疗后通过艾尔建眶下凹陷评估量表(AIHS)和全局美容效果分级(GAIS)对患者进行评估,同时患者自评治疗效果及满意度,并记录不良反应。结果治疗后AIHS评分改善率为94.59%(35/37)。GAIS量表中,医师评估达改善程度的患者为100%,患者自评约91.89%(34/37)达到改善。患者对治疗效果的满意率为91.89%(34/37)。5例患者出现淤青,1例出现丁达尔现象;无患者术后出现局部水肿,亦无感染、血肿、过敏、栓塞等并发症。术后6个月随访时35.14%(13/37)仍较治疗前有改善。结论皮下填充MCLHA改善眶下区衰老安全有效,可作为泪槽沟及下睑袋患者的非手术治疗选择。Objective To assess the efficacy and safety of subcutaneous injection of micro-cross-linked hyaluronic acid(MCLHA)in improving infraorbital aging.Methods From March 2022 to June 2023,37 patients with both tear trough deformity and eye bags were recruited at the Dermatology Hospital of Southern Medical University.The filling treatment plan of MCLHA in the infraorbital region was determined according to the classification of tear trough deformity.After the treatment,the Allergan infraorbital hollowness scale(AIHS)and the global aesthetic improvement scale(GAIS)were used to evaluate the efficacy.Meanwhile,patient self-evaluation of the efficacy and satisfaction,and adverse reactions were recorded.Results After the treatment,the improvement rate of AIHS scores was 94.59%(35/37).The improvement rates of GAIS scale by physicians and patient self-evaluation were 100%and 91.89%(34/37),respectively.The patients′satisfaction rate was 91.89%(34/37).Bruise occurred in 5 patients,and the Tyndall effect was observed in 1 patient.No patient had either postoperative local edema or other complications such as infections,hematoma,allergy,or thrombus.At the 6-month postsurgical follow-up,35.14%(13/37)of the patients still showed improvement compared to the pretreatment.Conclusions Subcutaneous injection of MCLHA is a safe and effective method for improving infraorbital aging,and can be regarded as a non-surgical treatment option for patients with tear trough deformity and lower eyelid bags.

关 键 词：眶下区衰老 微交联透明质酸 泪槽沟 下睑袋 

分 类 号：R47[医药卫生—护理学]